But if it should continue on for more than 2 weeks, get really severe or if you feel like you may be having an allergic reaction (hives, swelling of throat, heart issues) then it's time to get a hold of your LLMD!
Otherwise, welcome to the wonderful world of herxing!
I would greatly encourage you to take a look at the detoxing suggestions in the "New to Lyme?" thread and either start doing some, or if you have, increase what you are doing. This should reduce symptom severity after a few times of doing it.