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any good methylation reads?

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Posted 1/1/2015 5:40 PM (GMT 0)
I suspect this is something I need to learn about. And I've been putting it off since its all new to me and sounds complicated. What little I have read, leads me to believe this possibly runs in the family.

23andme MTRFR resulst should come in later this month.

Its best if I start out with the basics if i can, my lyme brain doesn't retain lengthy in depth reading very well anymore.

Any suggestions would be appreciated.
Posted 1/1/2015 6:10 PM (GMT 0)
For layperson-friendly info on methylation:

http://suzycohen.com/articles/methylation-problems/


For very comprehensive info about MTHFR mutation:

http://mthfr.net/
Posted 1/1/2015 6:39 PM (GMT 0)
Hi astro—

I think it's critical to uncover any methylation roadblocks when detoxing is such a critical part of our healing so kudos to you. It is like diving into quantum physics, but like anything we lymees have committed to, the more you read the more you understand. And for me, there is a tipping point at which everything finally falls into place and then I don't have to try so hard to get the basics. Up until then, it can be painful. ;)

cd's sites are most useful—good post. I also strongly recommend /www.nutrahacker.com for interpretation of your 23andme data. The full report isn't free but quite useful. The other free services I tried were a little disappointing.

I'm in the process as we speak of trying to figure out what to do with this wealth of information ;)
www.healingwell.com/community/default.aspx?f=30&m=3284903
so I'll be sure to post about my journey.

And as I mention in my thread, it can be overwhelming to know so much and so little about what to do with what you know. For me, I'm deconstructing it, prioritizing it, and putting some of it on the back burner until I can find a professional to help me out or until my brain can function a little better to do my own research.

Good luck!

-p
Posted 1/1/2015 6:41 PM (GMT 0)
Also—

Early on, it was quite helpful to cruise Youtube looking for methylation, MTHFR, detox videos. Some of them were quite good. Some of them were confusing. It was nice, though, to lie back on my pillow and listen to the videos. Then I would replay them while I watched. It's like compartmentalizing the information and filtering the stimulation—aural first, then visual… helped manage the "noise" if you have a problem with that like I do.

-p
Posted 1/1/2015 8:55 PM (GMT 0)
Put your methylation results in knowyourgenetics.com - it's free, and you get an interpretation and protocol customized to you.

For understanding more about methylation, I highly recommend reading Dr. Yasko's "Autism: Pathways to Recovery"
Free download at www.dramyyasko.com
or read (free) online at www.dramyyasko.com/resources/autism-pathways-to-recovery

mthfr.net also has excellent info.
Posted 1/1/2015 8:58 PM (GMT 0)
Thanks both of you.

I'm going to take this in slowly as my brain is kind of to fried to process this stuff right now.

If that nutcracker simplifies this for $50, thats what I'll do.

I am lucky to know a Dr (with own clinic, good for time))that is into this methalation stuff and everything on 23andme. Guess I'll find out just how much the doc knows.

And if theres any more good sites that others know about, feel free to let me know.
Posted 1/1/2015 9:07 PM (GMT 0)
Since you asked about "non-milk-thistle" types of detox on another thread, I share below a useful link I found recently (and posted elsewhere on here but figured you might like having it on your thread :)

http://www.huffingtonpost.com/leo-galland-md/why-you-need-to-detoxify-_b_706106.html
Posted 1/1/2015 9:14 PM (GMT 0)
See my reply to your "milk thistle" question in the "ANSWERS" thread: www.healingwell.com/community/default.aspx?f=30&m=3284903

Also, here's another methylation link:
www.heartfixer.com/AMRI-Nutrigenomics.htm - it is packed with info, and every time I read it, I learn something new (and I've read this page numerous times). This is a good one to share with your doctor.
Posted 1/1/2015 10:08 PM (GMT 0)
Raz-

That methelation map on : www.heartfixer.com/AMRI-Nutrigenomics.htm .............is pretty cool.

I had an introduction to several of these "maps" last year from the Dr thats into this stuff.

That visit made my head spin!
Posted 1/2/2015 12:44 AM (GMT 0)
Razzle—
When you say "put your methylation results" into the Yasko site… what do you mean? I think you'd need to have your 23andme data interpreted before you can fill out Yako's table. Otherwise you'd have to scan through the 550,000 or so SnPs produced by 23andme and find each one that is on her questionnaire. If not—what am I missing?
Posted 1/2/2015 12:56 AM (GMT 0)
Just had an idea… you can convert the 23andme .pdf file to a Microsoft Word .docx (with the right software like Acrobat or use the free online service) and then in Word do a search for the exact SnPs.


-p

Post Edited (Pirouette) : 1/1/2015 6:11:43 PM (GMT-7)

Posted 1/2/2015 1:45 AM (GMT 0)
ok....I came across a lecture for professionals, but i think a lay person can understand it. I'm pasting the link with the audio lectures....you have to scroll down to march 27/ methylation. it's an audio.

here's the link.
http://catalog.designsforhealth.com/library/2013-Discussions

Let me know what you think
Posted 1/2/2015 2:00 AM (GMT 0)
mthfr.net might be a good resource.
Posted 1/2/2015 11:14 AM (GMT 0)
If you open your 23andme result pdf, then you can press ctrl-F to bring up the search box. Type in and search for each SNP listed on the knowyourgenetics.com Methylation Pathway Analysis page (need to make a free account with knowyourgenetics.com first). Then enter your result and search for the next SNP, etc.
Posted 1/2/2015 3:30 PM (GMT 0)
As far as interpreting 23andme - if this is the easiest way :/www.nutrahacker.com

thats what I'll do. It is $50, but my brain is taking a tole right now, hoping this passes soon.
Posted 1/2/2015 3:52 PM (GMT 0)
astro—
Yes, nutrahacker is a SNAP (no pun intended).

But, Razzle piqued my curiosity with Yasko's site so I am going to pursue that as well… I've grown curious what the differences are. I already filled out half her list using the Nutrahacker results. So will now try Razzle's search tip and complete the answers. Thanks R!

-p
Posted 1/6/2015 3:17 AM (GMT 0)
Thanks Razzle, of course Preview has a search function! A "duh" moment for me.

So, I put my results into Yasko's site. Out of 10,000+ pages of DNA codes that 23andme provides you, Yasko's lists 7 that 23andme didn't provide. Interesting.

-p
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