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Reaction to Tinidazole?

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Posted 2/25/2015 6:37 PM (GMT 0)
So, I added Tinidazole month ago - pulsing two days per week 500 mg twice daily. Also on Ceftin.

After two weeks, I had a good week - 4 decent days in that week. But, now 4 weeks later, I'm not as good. More pain, nervous system crap....

Is it possible that the Tini is busting cysts and the Ceftin isn't able to quite keep up to it? And that's why after two weeks I was pretty good, but now, I'm feeling worse? Does busting open the cysts create a higher bacterial load - even if they were there prior to the busting?
I understand herxing...but this seems more like I'm just worse....any ideas?
Posted 2/25/2015 7:06 PM (GMT 0)
I was also pulsing Tini two days a week. Going back and looking at my daily sx log book I had worsening GI issues every 4 weeks or so, but intensity reduced as each month passed by down to no reaction after four or five months. Don't know what more to add we are all react a little different. Hopefully it will pass and if you keep a daily log you may see a pattern and some improvements.
Posted 2/25/2015 7:14 PM (GMT 0)
Girlie... The tini just kills the cysts. This was shown in a few laboratory studies. Once they break open the contents inside of them are mostly already dead and the contents are unviable.
Posted 2/25/2015 7:14 PM (GMT 0)
Thanks Tickbite - Been in treatment 7 months, and I still find myself questioning it all. I'm usually a decisive, black and white kind of person. This is really throwing me for a loop.

I thought since after two weeks, i was having more good days than ever...that it would continue. So, when I got worse on week 4 of Tini - I got worried.

I stopped biaxin a while ago (maybe 5/6 weeks ago) - and am still on Ceftin. So, of course, when i had more bad days, I thought uh-oh it's because i stopped biaxin and my bacterial load is increasing....
Posted 2/25/2015 7:22 PM (GMT 0)
So, according to Burrascano - end of week 3, week 4 are the worst herxes for a lyme treatment. Since you started the tinidazole recently, I would attribute the yucky feelings you are having towards Tinidazole being an effective treatment for you. I have been on tinidazole for over a year - herxing for me consisted of major fatigue (sleeping every day for a month just about!) as well as all this nerve stuff - stabbing, twitching, tingling, that went away about 3 months into treatment and has not come back. But in the beginning it felt like it was literally every 30 seconds of some random nerve something or other. My dosage has been 2 weeks on 2 weeks off of 500mg 2x a day.
Posted 2/25/2015 7:36 PM (GMT 0)
LP - oh, I thought the Tini busted them, and spit them out into my blood and another antibiotic had to kill them....so good to know the Tini is slaying them, after busting them open.

SLML - It's interesting the week 3 and 4 - cycle. Up to this past month, I have never had that cycle.
And because I had one of my best weeks ever after two weeks, I thought that meant a 'new normal' for me.
So, I guess it's possible that I have a lot of cysts in me....and maybe that is partially what's responsible for my slow progress (7 months and counting).

Well, I hope the Tinidazole is going to work for me...maybe it's been the 'missing link'....although i think it could also be bartonella....I guess time will tell and I haven't given the Tini much time yet.

Patience....
Posted 2/26/2015 3:38 PM (GMT 0)
I am doing my tindamax today for 4 days, suppose to take 2000 mg at once, I am going to break it up and do 1000mg now and 1000mg tonight. I don't work tomorrow so started it today in hopes of it not effecting me till I'm done working today at least, then I can just veg out.

Seems like my herx on Flagyl was a headache and fatigue, only took tindi one other time so I can't remember.

So according to the other post, maybe it won't get me for a few months.
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