So Confused by 23andMe Results - MTHFR and Other Mutations

Hi GraceNJ

I am going to do by best to sort through your mutations and I am getting my information from this website:

http://www.heartfixer.com/AMRI-Nutrigenomics.htm

He looks like a great doc so if you have finances he may be a good one to see should you struggle with sorting through them all.

1. CBS + BHMT mutations = BIG AMMONIA DETOX PROBLEM
Because you have these mutations, you have to bring down ammonia levels before supplementing your MTHFR mutations. This is done by zeolite and others have used yucca and activated charcoal. Looks like you may have to do this for a month or two before adding in for your other mutations. Also it is recommended to reduce dietary protein to cut down on ammonia levels as well.

2. COMT + VDR mutations are related to your ability to tolerate methyl groups (methyl b-12 and methyl folate). You will not be able to tolerate alot of methyl groups and because methyl folate has to be taken in methyl form then b-12 most likely should be taken in the hydroxy form (Perque a good brand). VDR also means you are low in Vitamin D.

3. MTRR means you are using up b-12 rapidly. This is supplemented by taking hydroxy b-12 in your case.

So as far as supplementation:
1. Zeolite, Charcoal or Yucca to detoxify ammonia first.
2. Hydroxy b-12 (maybe adeno b-12 too)
3. Molybedum, CoQ10, Phosphatidyl Choline, Vitamin D.
4. Lastly - methylfolate (begin @ low dose)

That is a really simplified version.
Read the info in the link to really understand your mutations. He goes in depth and the information is really good.

Post Edited (SLML) : 2/27/2015 5:59:33 PM (GMT-7)

GraceNJ

Happy to help

Out of curiosity, what are your main symptoms you struggle with from lyme disease (in light of mutations)?

Try knowyourgenetics.com - put in your methylation gene results from 23andme and it will give you a report consisting of the supplements needed for each mutation.

To learn how to correctly implement the supplement lists, read Dr. Yasko's book: www.dramyyasko.com/resources/autism-pathways-to-recovery

Bringing up an old post, if my questions are inappropriate to ask on this thread, please let me know and I’ll do a separate one

I just started on Nystatin and was about to order Molybdenum but was reading about CBS mutation and have been wanting to do the 23andme, but this older thread provoked perhaps a dumb question.

I read the suggestions SLML gave. Which made me think about supplementation. Would it be better to be off some supplements to have more of a natural clean slate prior to testing....or is it imprinted no matter what? Wondering if it misconstrues anything

Oh and am I making the right assumption that most people are getting the $199 test?
Was going to get the 2/$99 deal. Me, for medical reasons, the other for my half sister who never met her father.

Thanks

To get the genetic data you have to do the $199 version. We just did it for DS and then I ran it through Promethease and GeneticGenie and now need help similar to OP of this thread. So glad it re-surfaced!