In my opinion, it depends on how old the infection is. If it's caught before symptoms begin - yes, I think just raising the immune system is all that's needed. Buhner believes this as well, which is why he says to use Astragalus to avoid Lyme, and if you get bit, to raise the dose immediately. I'm currently "testing" this out.
But, so far so good!!
Once the person has started to show symptoms, things begin to get complicated, as different systems of the body are now involved. Just raising the immune system might still work for some that only have Lyme, but if there are co-infections or any other kind of medical issue (low thyroid, intestinal issues, detoxing issues, adrenal issues and more), then they will likely need more than to just raise their immune system - but should heal fairly "quick" using some type of antimicrobial treatment.
Once the person has multiple bodily systems involved and the infection is chronic, well, the rules change. I don't believe anyone can heal without some sort of antimicrobial treatment. This can come in the form of pharma abx, herbal abx, Rifing, Colloidal silver (I guess, I've not done the research), or several other means of killing bacteria - and most of us do best when two or more different types of treatments.
BUT - I think that anti-infective treatments are only part of what is needed for anyone who has chronic Lyme along with co-infections. With the experience that I had personally, and what I've watched others go through, here is what I believe needs to happen for many of us to heal:
a)Detoxing - gene mutations, mold exposure and multiple tick-borne infections can all prevent us from detoxing well, but we must be able to get those toxins out of our bodies.
b)Supporting the body functions/systems. We have to have the body working at it's peak performance to heal from something as devastating as these infections. Supporting any gland, organ, body system that is struggling will allow the body to switch it's 'concentration' from just trying to function over to healing.
c) Raise the immune function. Many legitimate Lyme researchers now believe that it's the lowered immune function that determines who gets chronic Lyme and who heals right away. We already know that Lyme lowers the immune function and when a person has Bartonella and/or Babesia, the immune function is further compromised, so to heal we must raise our immune function.
d) Lastly, oddly enough, are anti-infective treatments. Many of us have experienced treatment failures, so we can see that the treatments aren't the only thing we need to have - there has to be more to the equation, but anti-infective treatments are very important!! Lyme bacteria are one of the most complicated bacteria! Although it takes only hours or days for most bacteria to replicate, Lyme bacteria only replicates in the body every few weeks.
Please remember, that is only my personal opinion. All I want is to help people find whatever works for them.