Is anyone familiar with these gene mutations?

I just want to say that, yes, I plan to do some of my own research, but I figured I'd see if any of the people here who've had genetic testing done through 23andMe, or elsewhere too, I guess, recognizes any of these as mutations they themselves have:

MTHFR C677T
VDR Taq
MAO-A R297R
MTRR K350A
COMT V158M
COMT H62H
COMT P199P
BHMT-02
BHMT-08

The MTHFR I know is a mean one. I've seen talk of it around here. What about the rest though?

Though, seeing as I got these through Genetic Genie, they're only the mutations relating to methylation, right? Maybe? That sounds passable, Antonio.

That said.. , I must have more! Oh no! Guess I'll find out soon enough.

Thanks for the input, those who bothered.

Okay, I'll look into those. Though, seems there's a supplement for all of the mutations. Tons of stuff listed on that Dr. Yasko's KnowYourGenetics site, after I put my data in.

Yes, I've been told my Vitamin D's low, here and there. It's never consistent though. Sometimes, the doctors would say, hey, it's low. Others, no mention. Leads me to believe it jumps around, or used to. I haven't had much blood work done in awhile.

Caffeine. Never been a coffee or soda person, even before.

Lots of stuff though, yeah. Trying to make sense of my Promethease results atm. It's a little too much.

I have the genes listed in order of magnitude, which I'm guessing means.. most important for me to know about, so it's kind of unsettling for this one to be on top. They try to reassure by saying how rare it is. Why is it at the top of the stack though? lol

rs12340895(G;G)
2 - 4 fold increased odds of developing V617F-positive MPN A Promethease user who has this rs12340895(G;G) genotype has reported that they have mastocytosis, a myeloproliferative neoplasm (MPN). But don't panic! Mastocytosis is listed as a rare disease by the Office of Rare Diseases (ORD) of the National Institutes of Health, which means mastocytosis affects less than 200,000 people in the entire US. To put it another way, 5 to 10 new cases are reported annually per million people. Since this rs12340895(G;G) genotype is carried by many people (e.g. ~10% of all Caucasians, or, over 30 million Americans), it's clear the overwhelming majority do not develop mastocytosis.

I've worried about that actually, after looking into the methylation stuff because of all the food and chemical sensitivities I've been having. Mastocytosis, MCD, all that fun stuff.

Anyway, gonna get back to looking through it..

Thanks!

Post Edited (NotQuiteAntonio) : 11/5/2015 2:41:50 AM (GMT-7)

I know virtually nothing about the gene mutations even though I had MTHFR testing and know what I need to do for my particular mutation (hetero C677T).

Still, I commend you, Antonio, for your continued efforts at trying to solve your health puzzle. I believe the answers are out there. Sadly, it seems this means more work for you because our health care system is inadequate.

We're rooting for you!!!

Please keep us posted.