Abundance of false positives in food antibody testing for patients infected with Borrelia / EBV

A new study may shed some light into why some of us seem to have lots of positive results when it comes to food antibody testing, that may lead us to believe we are allergic to all sorts of foods. It's not true, we are not allergic, it just happens that Borrelia antibodies are similar to some produced by people that have real food intolerance, thus when u run a food antibody panel you get false positives.

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In the last ten years or so, in my own clinical immunology lab, I have performed hundreds of IgG and IgM antibody assays for the detection of Lyme disease and viral infection. And in the course of processing the continual parade of samples, antigens and antibodies, I made a personal observation of a curious correlation.

I noted that patients’ samples with high titers of antibodies against the antigens of certain infectious diseases, specifically Borrelia burgdorferi, Epstein-Barr virus VCA, EBV-EA or EBNA consistently had significant reactions when tested against certain food antigens. These samples with high titers of antibodies against these infectious agents would react to 20-60% of tested food antigens. Conversely, samples with low levels of Borrelia and EBV antibodies reacted to only 5-20% of tested food antigens. What was the meaning of this correlation? With this in mind, I initiated this study in order to clarify the relevance of these antibodies to the food antibody testing that is currently performed in many laboratories for the detection of adverse reaction to foods.

The findings of this current study indicate that, indeed, some of the IgG immune reactivity test results reported by many labs for the detection of food immune reactions may be due to cross-reactivity with infectious agents, and, hence, could be false-positive.
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dx.doi.org/10.4172/2155-9899.1000359

So we should be a bit skeptic about the results of food intolerance/antibody test panels we run... (especially if they say we are allergic to foods that fall into the ones that cross react with Borrelia antigen, see the charts on page 4 of the PDF).

yeah and these diets are sometimes very limiting. Look at the chicken cross-reaction. It is sky high. So if you run a food panel you will find out you are allergic to chicken, turkey, grapes, peach, tomato, apple, blueberry, garlic, almonds, shrimp, red snapper, mustard ... come on, what are the odds !

My conclusion based on this study, is the antibody food panels in case of lyme disease are completely unreliable. Unless you KNOW you have an allergy to something, you ate that stuff and got really sick, repeated the test and got same result, then you should NOT limit your diet based on what theses food panels say... especially if they say you are allergic to 15 types of food...

Exactly mpostelnicu,

I asked my daughters Dr. in the clinic in Germany regarding testing for food allergies, and asked her because she used to get rashes when eating sweets in the school , when they had birthday parties for other kids.
The answer was to test her only when she is over with treatment because the food allergies would go away after treatment.
The LLMD that treated me had a large group of children with autism under treatment or treated and his opinion was to test at the beginning of treatment and then do together:diet, herbal treatment, HBOT, some Abx. treatment and psychological treatment altogether.And at the end maybe retest and slowly introduce the foods that are the culprit.(the ones that do that for their own children probably know to make the elimination diet and then reintroduce the allergenic food after 2 years of being on the diet, that is what I know from a homeopathic Dr.)

These are 2 opinions from LLMDs with good results in treatment.
My understanding is that borrelia and maybe chlamydia modify the immune system so that it reacts abnormally to food.Of course gut-health is important too.And by treating throughlythe infections allergies would go away.

Greetings and thanks for the always very good info mpostelnicu.