This is just an example of some of the problems we face. When looking at the link, hold your cursor on the boxes or rounded items and you get additional pathways. This is less than 1% of what is happening inside our body.
This is far too complex for me. There is no way a physician has time to learn this either, only lab people doing research have the time to get this deep. But remember that each of these reactions is dependent on substrates and pH. If you have a lot of inflammation, you will have a lot of acid and your substrates will be decreased. There are redundancies and negative feedback loops to help these cycles continue when we are depleted of nutrients, but there are so many reactions that it just seems our system can "bog down."
Things like this is why I always preach the importance of pH and trace minerals. They are the catalysts to keep these reactions occurring and when they don't occur, we are sick and unhealthy.
www.genome.jp/kegg-bin/show_pathway?ddi00400