Evaluation of a New Multiparametric Microspot Array for Serodiagnosis of Lyme Borreliosis

www.ncbi.nlm.nih.gov/pubmed/26731998

Those with more medical knowledge can weigh in on this, but it seems to be antigen testing still? Would that be effective in chronic lyme due to immune system not able to produce antigen response?

Correct, K07. The two tests they are talking about - Seraspot and the recomBead are both still looking for antibodies to be produced:

RecomBead:
"In routine diagnosis, the serological detection of Borrelia specific antibodies represents the easiest and safest method for the detection of a Borrelia infection.
Enzyme immunoassays like recomWell Borrelia are mainly used for screening. For confirmation of borderline and positive results strip assays like the recomLine Borrelia are approved and safe detection systems. The modern Luminex® multiplex technology integrates the advantages from ELISA and strip assays: detection of antibodies against individual antigens in a high-throughput system. The recomBead Borrelia 2.0 is using the approved and highly specific recombinant antibodies."

www.mikrogen.de/english/deutschland/products/product-overview/testsystem/borrelia-igg-20.html


SeraSpot:
"The SeraSpot MicroArray for Borrelia burgdoferi antibodies combines the standardized and
robust ELISA technique with the Microarray analysis in one single microwell."

www.arminlabs.com/content/forms/new-seraspot-lyme-arminlabs.en.pdf


The problem is that they aren't looking for anything other than MORE faulty testing methods though. Dr. Alan MacDonald actually has testing methods that don't rely on antibodies being produced, but he's being shut out.