Amoxi no effect = sign or patience?

Hi Brendoni -

1g of amoxi per day is a relatively low dose, which is likely why you're not feeling much reaction. He might be starting you off at a low dose to help your body acclimate with less herxing, especially if you're adding in another abx so this is very good for him to do for you.

But you should probably titrate up at 21 days at the latest - sooner if possible. Your MD should probably increase that to 3000mg to 6000mg per day, per ILADS (p. S9). Please talk with him about this:
www.ilads.org/lyme/ILADS_Guidelines.pdf

By "emotionally/spiritually the same" - what do you mean? Same meaning poor? same meaning no change since starting the amoxi?

-p

That is a low dose, but I took a couple of antibiotics and felt nothing for 28 days.

Lyme disease is not like any other illness. You don't take a medicine and start to feel better. It just doesn't work that way. It is a long slow process to getting to wellness.

I was on antibiotics, then switched to herbals and after months a few symptoms went away. It was so very slow.

Brendoni -

OK - thanks. That makes sense.

Lyme, bart, babesia and likely other infections can cause neurotransmitter imbalances - thyroid imbalances can cause neurotransmitter imbalances, GI problems can, hormonal issues can... it's all interconnected. The neurotransmitters are what drive your emotional states. What you describe is very common and sometimes gets worse with treatment because of the neurotoxins created by both the infections and the die-off. Sometimes it's caused by ammonia. This is another reason why a very wholesome, healthy diet is helpful in controlling inflammation and other issues in the gut, given the gut-brain connection and various ways that neurotoxins in the gut can find their way to the brain.

I've had the same symptoms since I was infected 19 yrs ago... but when I started on the Rocephin abx for lyme and also when I started on the vancomycin for bart 18 months later... each time the first 4-6 wks on these abx were absolute torture. It's one thing to be in pain or physically suffering. It's another thing to feel like you're losing your mind. I was terrified. The physical symptoms improved almost immediately on abx (I could actually walk again) but the psycho-neuro chaos was unbearable. Then it leveled out to more of what you describe, now I've made progress on top of that.

I recommend increasing detox as much as possible, titrating slowly to optimal protocols as you continue to increase your abx dose and add in more killing agents. Ideally, you want to have a good detox program in place before starting on killing agents. it's definitely not too late to start (I hope your LLMD talked w/ you about detoxing). There is a ton of info on this site.

Also, try adding in brain support and detoxes - Pinella and BurBur are very good - I've been on them since day 1 and several others here are using them successfully. My very lyme-friendly neurologist sees a lot of lyme patients and has determined that most of the pain and neuropathy symptoms are related to inflammation. That might also be an issue for you to investigate - you can also search here for anti-inflammatory remedies. I like Japanese knotweed and turmeric is also helpful. Please avoid all anti-inflammatory Rx like steroids, though - they will fight your lyme treatment which needs support from your immune system.

Omega 3 oils are helpful. I also take a supplement called Huperzine for brain support - pretty inexpensive, I get mine on amazon. My LLMD just recommended Enula for recent herxing due to treatment - haven't tried it yet.

Hope this is helpful -

-p

Brendoni said...
Thank you, this is what I had also read.

RE: emotionally/spiritually, I mean that while all the "natural" interventions so far have been able to limit my physical symptoms, I still remain quite emotionally and spiritually detached/numb – i.e. not excited, happy, joyful, funny – which is a very strange and rare condition for me, considering these emotions have always been natural to me. I've not yet found any way to help with this.

This is normal and part of the disease. Brain fog, anxiety, depression, ..... all symptoms.

What is sad is that you feel you have a grasp on what your symptoms are and boom! along comes one you have never had before. It will cause you to worry if you have gotten something else.

Lyme made me paranoid as heck. Just go with your gut feelings. That's what I did. If I was really concerned, I always went and got it checked out even further.

Be very good to your body as it tries to heal. Give it good stuff and you also need to give your mind good stuff.

It will be a slow journey to health, but you can do this. Patience is super important. And because you are unique, as we all are, you will probably have your own unique remedy. And the way you find what works for you will be trial and error. That is how most of us are progressing.

Keep asking questions. Lots of super information on this forum.

Are all of these various supplements listed above OK to be taken with antibiotics? Should any be taken far from antibiotics?

I don't know of any specific contraindications with Pinella, BurBur, JK and abx or antimicrobial herbs... But I do know some of the antimicrobial herbal tinctures are to be taken alone with buffer times because the tincture formulas are a group of herbs that act synergistically and you don't want to interfere with that.

Also, I like taking my detox tinctures, doing the other detoxing (baths, dry brushing, oil pulling) at least 1 hr after the abx so that they can be more effective at detoxing the toxins released by the killing actions.

And I take my binder at the end of the day as mentioned.

-p

Just wanted to add to the antibiotic information.


So, minimum 3000 mg preferably divided into 3 (not 2) doses daily. Amoxy has a half -life of one hour...so that's why the 3 dosing schedule.

Also, there is a medication called Probenecid that you can take - it will keep the blood levels of amoxy higher for longer period of time. It is an old gout medication...
Here in Canada - I had to have it made at a compounding Pharmacy.

Interesting.....^^^...

What is the success rate of the above treatment hdbitis.
How long? What is the dosage? AMOXI 2000mg daily +1000mg daily of CLARITROMICINE

hdbits - I just realized that was your first post on the lyme forum....so...little late, but would like to Welcome you here.

We encourage all new members to take a look through the thread at the top of the page titled: "New to Lyme?..Start Here!" It's packed full of useful information.


I'm sorry you have lyme disease, but glad you found us here. It's a great group of people - full of compassion and lots of knowledge here.

thanks, julymorning...I missed that question.

Well I am still awaiting for the answer....lol

What if you already took amoxi on its own. Can you re-inact that treatment above with amoxi and clari? You did not say how long and the success rate...