How quickly does Brucella reproduce?

I read several articles hoping to find that answer, but aside from learning more about it that worries me, this is as close as I could find to an answer.

"Intracellular replication of B. abortus and B. melitensis in the presence of 3-methyladenine
Previous studies have shown that incubation of cells in the presence of 3-methyladenine (3MA), an inhibitor of class III PI3K often used to block macroautophagy [23], impaired the replication of B. abortus[13] and B. melitensis[22] in HeLa cells and in RAW264.7 macrophages, respectively. These data are in contradiction with our results showing that both bacterial strains are able to replicate in Atg5-deficient MEFs. Therefore, we sought to determine the putative impact of 3MA on the replication of Brucellae in WT MEFs. First, we assessed the number of B. abortus-mCherry per infected cell in WT MEFs preincubated for 2h in the presence or absence of 10mM 3MA. As shown in Figure5A, this treatment had no significant impact on the number of bacteria per infected WT MEF. Similar results were obtained with WT MEFs infected with B. melitensis-mCherry (Figure5B). However, in this case, we observed a significant decrease (p < 0.01) in the number of bacteria per infected cell but only at 24h p.i. Next, we examined the impact of a pre-treatment with 3MA on Brucella replication in host cells using the gentamicin survival assay. Our results show that a pre-incubation of WT MEFs with 3MA does not impair the replication of both B. abortus and B. melitensis (Figure6 A-B)."


bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-014-0223-5

Not exactly a precise answer unfortunately.

I've read in several places that bartonella reproduces a big quicker than babesia which is every couple of days up to 7 days.

The thing you also need to consider not every type of bacteria is on the same reproductive lifecycle. You could get infected with several of the same species of bartonella that are in various lifecycle stages. For quicker reproducing organisms like bartonella and babesia it makes sense to treat near daily whereas Lyme less so.

Even with this said practitioners have different ways of approaching this (e.g. Jemsek's pulsing, some other do daily rifing to stay ahead of the reproductive lifecycle, etc.)

For bartonella and babesia I would treat near daily whether its herbs, rifing, etc. When I start my new regimen from Jemsek I'm going to continue to rife daily for babesia and brucella/bart.