Buhner milk thistle question

For some of you buhner veterans,
Buhner says in the babesia book take "milk thistle seed standardized (80%silymarin) capsules, 600-1200mg daily"

I got some gel caps that on the front of the bottle says 1000mg. On the back it says 4:1 extract but that it's 250mg of the extract equivalent to 1000mg of the whole herb. So..... How many of these capsules do I take?

I'm starting to get all of these things written down on a sheet and working out a dosing schedule. I'm starting with the cytokine disruptors and organ supporters first before I start the antimicrobial and immune remodulators. Easy stuff first that won't cause a herx. I'm still trying to wash out a nasty herx I got from a-bab before I start the antimicrobial herbs. I had made some good progress on the anxiety and sleep restoration and fear the a-Bab herx set me back.

Thank You,
David