Well, I just went to Imugen's site and read on their Lyme testing page - and it's not encouraging:
"Screening asymptomatic or nonspecifically symptomatic individuals in whom the a priori probability of Lyme disease is low (such as patients with chronic fatigue, headaches, depression, arthralgias, or back pain) is not recommended. A positive test result in such patients, even in a highly endemic area, may not significantly increase the post-test probability that these patients have Lyme disease."
"Clinicians are frequently confronted with patients presenting with unexplained febrile illnesses, rashes, swollen joints, or neurologic symptoms (such as cranial nerve palsies or suspected meningitis). There are also challenging patients with persistent nonspecific symptoms after being treated for well-documented Lyme disease, and patients who develop new symptoms raising the suspicion for re-infection. The combination of antibody capture EIA and immunoblotting (WB) in most cases can assist the clinician in assessing these situations and lead to the correct diagnosis."
And if that's not bad enough: "Most patients (~90%) symptomatic with B. burgdorferi infection are seropositive, demonstrating an initial IgM response best shown by antibody capture EIA. "
Which is totally false. I quit reading after that.
www.imugen.com/education/lyme-disease/