Hi coach1 -
The persister response is a risk generally regardless of which abx one uses. The persisters function as a component of the Lyme microbe, itself. This stealth characteristic of the modern Bb microbe is one of the reasons people are convinced the current epidemic can be traced to its engineering as a bioweapon…
One approach is to pulse the abx delivery with the intent that the Bb leave tissues and re-enter the blood stream for reproduction, allowing the abx, antimicrobial herbs and/or immune system to attack there.
I'm not sure about
the deptomycin - maybe others will chime in about
that abx. But vancomycin is given via IV generally for bartonella. It's not an oral tx for a systemic infection like the TBDs but it is given orally for c-diff. Vanco does have the effect of "reducing cell wall stiffness and slows down swim speed of Bb"
www.prohealth.com/library/showarticle.cfm?libid=30040But if one was going to go through the trouble of doing IV abx, most would do IV Rocephin for Lyme, not vanco.
-p