Nasty Herx from Rifampin yikes

Hi,
I'm on Rifampin now, week #3. 300mg twice a day. I have no idea what's going on. The first week I was doing relatively okay and now I have such a nasty herx. Neck pain, weak legs, headaches, anxiety, muscle pain, swollen joints... I do detox a lot and usually I try to tough it out, but this has been going in for more than two weeks straight. I just want to sleep and not move at all.
Anybody else had such a bad experience with Rifampin?
I thought it was one of the abx that dint make you herx that bad... Even Mepron and Azithromycin didn't bring me down like this.
Any suggestions how to make it through?
So sorry for the whining :/

Simone

Sorry Simon!

Rifampin causes crazy herxing. In fact my LLND had me start with 300 mg once daily (he doesn't usually have me start out on half doses of the abx) because it's a doozie.

I suggest you take a couple days break...if detoxing doesn't help alleviate your herxing.

What is the other antibiotic you're taking with it? Azithro?

Oddly enough I did not herx from Rifampin. I experienced the anxiety, the orange pee, even rare spleen pain but no herx and no relief in the short 6 weeks I was on it.

Since stopping the spleen has felt better although I believe it is slightly enlarged still.

What I did find is I think it helped me reduce the Fluconazole. I am down to once weekly.

Unfortunately I had to stop the Rifampin. My Lyme is weird and my Bartonella does not cooperate.

If it werent for very specific symptoms that correlate to Borellia and Bartonella, I would be doubting my infection.