Low Globulin Levels

Hey all, my blood test results came in today and my globulin levels are on the low side at 1.5 (1.9 is the low threshold for normal). Last month globulin was also at 1.5, and the month before that was 1.8. I don't have any tests prior to that. My LLMD said this was puzzling and not something he would normally associate with Lyme and coinfections, or antibiotic treatment. He said as long as it doesn't keep going down he wouldn't consider it alarming, although he did want me to follow up with my PCP to see if they can figure out why these levels may be low. For the most part everything else in my bloodtests looked pretty normal, except a CD57 a little on the low side as well.

I wanted to ask if anyone else has had low globulin levels or may know what is causing them. I'm taking Cefdinir, Azithromycin, and Minocycline and have actually been feeling pretty good this week. I'm hoping that whatever the problem is, it's either not serious or something I can take care of before it gets any worse. Thanks for the input.

It's part of the basic metabolic blood test panel, and is a measure of protein concentrations in the blood. The problem is that a low level of such a generic test can mean a bunch of different things, some serious and some not. Mine isn't TOO low, but I'm gonna get it followed up with more specific tests just to be sure. I've been having loose stool lately, probably from the antibiotics. I wonder if malabsorption of nutrients is the problem. Guess that's another question to ask the doctors. My LLMD told me he wasn't overly concerned about it, but he would be if it keeps dropping. In the meantime, I'm going to have more blood and urine tests done.

I think the urine test is to see if I'm urinating out the protein I'm supposed to have in my blood. If I am that'd mean my Kidneys aren't filtering the blood properly. In any case, whatever the problem is I hope it isn't serious. From what I can tell, elevated globulin is a more common problem.

I saw some of your posts. But the question is even if we recognize that low globulin levels are indicative of an under functioning immune system, what can we do about it?

I just posted on the other thread....I never paid attention to the globulins before..