Hyper Sensitive to Coffee and Alcohol (Genetic Testing)

This morning I drank a cold brew coffee and I've been feeling awful since. I get extra fatigued, my heart beats hard, and I get really dizzy and jittery. I have noticed that I feel like this if I drink even a little bit of coffee. I even feel cruddy after decaf (still has some caffeine in it). The same happens when I eat chocolate.

Is this because of a genetic mutation or because of the chronic infections that I have? (Lyme, bartonella, mycoplasma and CPN)

I am thinking about doing 23andMe gene test to see if maybe I have a mutation that doesn't allow my liver to properly detox caffeine.

It sucks because I love coffee so much and going to coffee shops downtown. Its my weekend routine. Sometimes I get tea and don't feel as bad.

The other night I was at a bar and sampled a beer and literally felt horrible the next day. I didn't have more than 3-4 ounces but felt like I had a massive hangover. Bad headache, fatigue, brain fog, dizziness.

Are these two things pretty typical with Lyme and get better after getting rid of infections or does it sound more like a mutation and if it is a mutation could the mutation also be causing a lot of my other symptoms?

Even if I did do 23andMe and found something wrong, I feel like it would be hard to find a doctor that would understand my results.

I know this is kind of all over the place but any input is appreciated!!

I'm not sure... but I think 23andMe gene testing would flag that? So maybe this is a good option..?

astroman said...
Histamine is not in 23andme data as far as i found.

This is the link I found. Can you confirm whether or not this would tell me good info on histamine issues?

/www.geneticlifehacks.com/histamine-intolerance-genetics-part-2/

astroman said...

NicHostetler said...

astroman said...
Histamine is not in 23andme data as far as i found.

This is the link I found. Can you confirm whether or not this would tell me good info on histamine issues?

/www.geneticlifehacks.com/histamine-intolerance-genetics-part-2/

Well.........I just learned what ABP1 gene is. I didnt know it effects the DAO enzyme which..... breaks down histamine.

My 23/me is 4 years old, so they test more varients as time goes on.

Of those 6 variants listed in your life hack link, my old 23 raw data tested tested 5 of them. I do have double copies of one gene, even though i had histamine tested by Quest labs- its a normal test. My histamine levels were normal, so I guess my double gene was not expressed at that time.

I can and do drink coffee again, but stick to lower acid coffee.

**Back when coffee gave me the jitters was also when my adrenals were toast.** I was wired and tired all the time and coffee sent me through the roof- even with good histamine levels.

If you have lab coverage with health ins, it will cover the Quest histamine test. You could also try some over the counter anti histamine and see if you feel better with it.

How did you get your adrenals back in check? I would loveeee to be able to enjoy a good cup of coffee without knowing I would be sick for the rest of the day. Is there a good test for adrenal function?

23andme has stopped reporting some important genes (effective last year). Ben Lynch is working on a new genetics test that will be more inclusive. From what I know DAO is histamine gene. This is a great interview:

/www.betterhealthguy.com/episode70

Im DOA deficient AND have the gene mutation(s). So consuming TOO much coffee, caffeine, or even foods that require DOA, causes my histamine cup to overfloweth!!! I can drink a cup of 1/2 caff each day, but cannot tolerate any alcohol at all! I take two doses per day of loratidine(claritan), and the digestive antihistamine pepcid.

The only thing is, when I was in college (just a couple years ago), I was able to drink lots of alcohol with no issues. Maybe a slight hangover from a pitcher of beer. I'm pretty skinny too..

So why no do I have a bad reaction? Can histamine issues kick in that fast? Can they ever go away?

astroman said...

NicHostetler said...
The only thing is, when I was in college (just a couple years ago), I was able to drink lots of alcohol with no issues. Maybe a slight hangover from a pitcher of beer. I'm pretty skinny too..

So why no do I have a bad reaction? Can histamine issues kick in that fast? Can they ever go away?

First step is to get your histamine tested.

Guessing gets us nowhere and often on the wrong track and in worry mode. You can pay for this test and go to labcorp for the draw without a Dr.

Anything that might be gene influenced can be switched on and off by illness, infection ect. This is gray area that should have better definitions in the future.

Alcohol also feeds yeast- candida ect.

Ok, I know I did a morning spit cortisol test in the past and it was fine, but yeah I'll get my histamine checked. Where do I order it?

astroman said...
Have a Dr? Insurance

No?

then -youll have to goggle histamine test. Direct labs is a good start.

(it is an insurance covered conventional medical test - nothing weird )

I have a doctor and great insurance. Insurance covers 80% of my labs so if there was a lab that could take insurance without doctor order then that would be awesome. My doctor would probably order it but she charges every time I call her.