Primaquine/Coartem/Stevia a Possible Cure for Lyme Babesia

jb1994 said...
Yep that was what I was referring to

The quinolines (vs the fluoroquinolones) drugs that Charlie is referring to aren't the same ones - mefloquine and chloroquine are two that I saw mentioned in the article (causing psych symptoms)

Girlie said...
Fluoroquinolones have several black box warning including one for CNS damage

“The fluoroquinolones have the unique ability to penetrate your blood-brain barrier, entering your brain and damaging your central nervous system.”

Quinolones are in a different class than fluoroquinolones, fluoroquinolones are antibiotics, while quinolones are antiparasitics. I know both are probably derived from similar compounds, both still being quinolenes, sure both can do damage to the CNS regardless. Good thing was I was on primaquine for short period...

I think instead of waiting a few weeks, then following up with pulsing disulfiram, I need to wait a few months let my system recover, then see where I'm at. Probably why my babesia symptoms were returning like the plague was disulfiram, which wakes up dormant cells. I have this mentality that I'm going to kill every last persister cells, never going to happen. I think I need to just let my immune system take over...

What I did was stupid, but again, confirmed what I suspected, that I have a resistant dormant form of babesia. And until I hit that parasite with the propper drugs, I was basically getting nowhere.

My ankles and wrists loosened up, which I didnt realize were stiff before that. My fatigue went away and I was more clear headed than I've ever felt before.

I'm still curious why no LLMDs are using this drug, when it's the only antiparasitic on the market that eliminates the hypnozoites, the dormant liver form of malaria.

Probably could of prevented a lot of suicides and deaths over the years.

https://en.wikipedia.org/wiki/primaquine

Wikipedia said...

Primaquine is primarily used to prevent relapse of malaria due to Plasmodium vivax and Plasmodium ovale. It eliminates hypnozoites, the dormant liver form of the parasite, after the organisms have been cleared from the bloodstream.

Girlie said...


The quinolone (vs the fluoroquinolones) drugs that Charlie is referring to aren't the same ones - mefloquine and chloroquine are two that I saw mentioned in the article (causing psych symptoms)

Nice correction girlie.

From what I'm reading, it's both the toxicity load from the die off of malaria/babesia along with the toxicity of the drug which can cause some serious psychiatric problems which I was having.... However, I was having those lyme herxing seizures after the primaquine/coartem protocol, not during.... After waiting a couple weeks, then following up with just cannabis/cbd oil. I was having paranoia/anxiety/racing heart/herxing etc...

I think I did have one huge herx at the end of the primaquine cycle though that put me in the hospital first...

Now is it because my CNS is now sensitive to other drugs because of coartem/primaquine. Or is it just herxing because I took a major coinfection out of the way which made borrelia vulnerable.

Probably stupid to follow up with cannabis, which can cause psychiatric problems too if abused.

After taking cannabis out of the picture, I've just been using disulfiram... Herxing like crazy and babesia symptoms.

Probably just best to wait a few months before I do anything, send my bloodwork out to igenex, see what comes back for babesia.

I guess deep down, I'm little worried to lose my gains with babesia. Borrelia has a slow life cycle, but with babesia, if you dont knock it out effectively, parasite just keeps coming back like Malaria.

Hey I guess my health and mind is more important, so time to just try to heal, build up my immune system, go from there.

Sheekster said...
Charlie - The JSC clinic is great. I see Kim F there. I recommend her as she is the longest standing PA / NP at the clinic.

Appreciate the insight... I'm going to go check out my old local LLMD, but I plan to call the JSC clinic soon. Maybe even Dr. H...

I'm tired of fighting the disease alone, risking my health... Sucks going out of state, but probably worth it.

Post Edited (Charlie55) : 4/14/2019 12:41:28 AM (GMT-6)

Girlie said...


If you pull a positive Babs test from Igenex....you know.
If you pull a negative Babs test from Igenex....you won't really know.

I havent been following the recent tests, what's the most accurate for babesia in modern day? Has anything changed?

FISH from that Fry Labs? FISH can identify a specific species right?

Or just do Igenex?

I suspect doing bloodwork after doing primaquine, which may wake up dormant forms of babesia, could really increase the accuracy of the test. Just guessing...

I remember reading that taking biofilm busters in some article can increase the accuracy of borrelia test.

Quinoline = primaquine, chloroquine, hydroxychloroquine, tafenoquine, etc
Quinolone = fluroquinolone. cipro, levaquin, etc.

The difference is the I and the O.

Charlie55, glad you are doing better. I am a little confused about the term "dormant Babesia." Babesia is a piroplasm and it has a life cycle that has stages. Some stages may take a little more time, but at no time is it considered dormant. Any info you may have on this would be appreciated.

Dude, shoot me an email if you want to know about carbon monoxide build up. That is what happened to me.

Is "floxing" related to fluoroquinolones? I remember seeing that word pop up on the benzo boards.

Quick update, another chronic lyme patient I've been in contact with has tried primaquine, within two weeks her white blood cell count increased up to 8,5! Her avarege WBC is around 4 and tends to be lower while on antibiotics.

Also, in 10 years I can now tolerate whole milk and lactose without having a reaction...

Woke up drenched it sweats today feeling absolutely horrible, but after eating, then doing some yogurt and probiotics, I feel great. Best I've ever felt. It just seems the babesia symptoms are coming and going... Also seems just doing probiotics/milk/yogurt/probioticpill can cause herxing for me.

Also a lot of that mucous that has been in back of my throat for 10 years has almost cleared up.

Herxing is very severe being on primaquine/coartem protocol, but I sure hope many Doctors start using these drugs to help a lot of chronic lyme patients. There's times when I thought it was all the drugs and I was overdosing, I suspect it's just the toxins from herxing. The amount of toxins that build up in your head from coartem is unbelievable... Remind you both of these drugs cross the blood brain barrier, something like Mepron has a hard time doing. How would you ever be able to cure Babesia if it doesn't cross the blood brain barrier?

There's times when Coartem/Daraprim made me stay up 4-5 days straight without any sleep, I was gasping for air, dry heaving, puked once. It took 4-5 days of constant detoxing and being of this drug to finally get some relief, once I did, it was the best I've ever felt. I think one day I was in and out of the bath tub 20 times, the water bill is probably going to be enormous. I started to just keep water in there, then drain it a little, then fill it up with some warm water to heat it up again.

It sucks, because treating Babesia with Coartem also seriously curbs your appetite, I think I've lost 15-20 lbs while being on this protocol. Doctor supervision is a must, but problem is, other than Dr. H, who treats with Coartem? Even Primaquine?

Here's an article that explains what helps the severe toxins from herxing and coartem.
https://www.naturalpedia.com/coartem-uses-health-risks-and-side-effects-at-naturalpedia-com.html

naturalpedia.com said...

Food items, nutrients that may help with the side effects of Coartem
Fever is a common side effect after taking Coartem. There are natural food items available to reduce symptoms of a fever and ease discomfort during treatment.

Water – Having a fever means that the body is losing water through perspiration and sweat to fight off disease; drinking water can replenish this and bring the body’s internal temperature down
Juice – The vitamins and antioxidants found in fruit and vegetable juices can help boost the immune system while replenishing lost fluids
Tea – Linden, willow bark, and black elder teas have fever-reducing properties, especially when these are served cold.

I'm just going to keep pounding dairy, maybe do a lot of Vitamin D, also probiotics. Hope for the best with remission.

I plan on seeing a LLMD soon, go from there...

$3000 to start of with Dr. H, $1000 to start off with Dr. J... Are there any good solid well educated LLMDs on Babesia in or outside of Michigan? That Dr. J in Maryland might be worth calling, I remember him being in Monsters Inside TV show for Babesia. Maybe he's more reasonable... http://lymemd.blogspot.com/

It's rediculous it's 2019 and I'm still in the same predicament I was 10 years ago... I honestly don't think any of the local LLMDs in Michigan have changed their protocols at all...

And I'm scared to even explain to any of the LLMDs in Michigan the protocol I've been on, probably would scare them. None of them are even close to what drugs and biofilms busters Dr. H and Dr. J are using, I'm not sure how it is in other states, but the lower level LLMDs are seriously trailing behind. I think a lot of them scared losing their license and liability still. The more potent drugs cause serious herxing that leaves many LLMDs in the emergency room, then the first think the Emergency Doctor and Nurse asks, who's your Doctor.... This has got to change in the future!

Post Edited (Charlie55) : 4/16/2019 3:28:22 PM (GMT-6)

Sheekster said...
Dr J uses coartem. I am going to be taking it as part of my babesia protocol in 1.5 months. Go to Dr J man. I listened to a live stream with the other Dr J you reference and I wasn't impressed at all. Dr H and Dr JJ are way ahead of him in terms of treatment and understanding.

Thank you so much for that important information Sheekster... I didn't know if Dr. J had used coartem or not... That makes me lean towards his clinic...

I wonder what Dr. H charges after the first $3,000, is it just $200-300 a visit?

I honestly can't believe I can drink milk again, lol... Thought I'd never see the day!

Post Edited (Charlie55) : 4/16/2019 4:02:45 PM (GMT-6)

Sheekster said...
Dr J uses coartem. I am going to be taking it as part of my babesia protocol in 1.5 months. Go to Dr J man. I listened to a live stream with the other Dr J you reference and I wasn't impressed at all. Dr H and Dr JJ are way ahead of him in terms of treatment and understanding.

I didn’t know Dr J used Coartem - that’s the Pharma Art derivative with another Med?

Charlie - unless it’s recently changed Dr J is a bit less for initial consult.
You can email me for the follow up appt costs if you’re interested.

I don’t really want to post it here - (altho I probably have before )

Your appts will be a few months apart (starting with 2 months, then 4 months and then 6 months.)

Keep hanging in there Charlie! I'm supposed to do another pulse of coartem this weekend. Hits me hard every time, herx lasts for about a week, puts me in a dark place mentally with the various symptoms and psych stuff. But yeah, after I get over the hump I feel soooo much better. Has been an incredible drug. When the herxes get bad (and it has happened with coartem) I get terrible insomnia as well. It's quite maddening, my body feels wired/tired and lots of feelings of doom and feeling overwhelmed. Quite unpleasant to say the least.

And thank you guys for pointing out the info on primaquine! very helpful.

I'm not sure in regards to glutathione, but Dr H tells his patients to take pretty high dose whenever they are herxing hard. If I recall correctly 8 pills 2x day, I can't remember the brand though some kind of liposomal glutathione.

"$3000 to start of with Dr. H, $1000 to start off with Dr. J... Are there any good solid well educated LLMDs on Babesia in or outside of Michigan?"

Charlie - what's included in the 3 grand? Is there testing done....or is it just the physical exam, his evaluation of your symptoms...?