Anyone large number of blood counts drop out?

Had a pretty decent day yesterday, then came in and saw my blood tests from hematologist. Shouldn't have looked.

I've had low red and white blood counts low normal or drop to low levels, but this time many have gone south - more than I've ever had. To list low ones: WBC 3.0, granulcoytes 1.98 lymphocytes .80, mononcytes 0.17 RBC 4.02, RDW 10.6, MPV 7.2, Manuel eosinophils 0%.

Also - haptoglobin (first I've seen this) is very low at 11mg with 34 low normal, and kappa free light chain still high at 22.9 (19 is high normal). Has anyone had a blood test this "off?" I have been concerned about autoimmune and know I have some form of it, though almost all tests for it come out normal.

Waiting on EBV latest numbers. As most know, EBV can cause autoimmune, but it can also lead to cancer, which is my deep concern here. That is not to scare anyone because I am only concerned based on the blood test. I went through a bone marrow biopsy in 2012 and another in 2017, but am concerned with quick rise in symptoms that has happened.

Sorry to go into so much detail. It was enough for hematologst to order more tests. In addition, I've had a daily fever, mostly in afternoons, for more than a year and a half. Last few months have had large lymph node on left side of neck that gets pretty big and sometimes goes down smaller, but it's always there.

Any thoughts or experiences are appreciated. Have gotten so I do not want to see another doctor or take another test because of psychological stress it brings.

I'm so sorry, running wild. This all sounds terribly stressful. I have nothing helpful to offer, just commiseration. I just filled out new patient paperwork for a hematologist, who works in oncology, which is just so freaky - answering all these questions about cancer. I understand why you are freaked out. On the one hand, cancer is terrifying and occasionally fatal, but on the other, it's often more treatable than Lyme and co-infections! That's dismal optimism, I realize.

I have chronically high EBV numbers, too, which my doctors seem to find alarming. The numbers never seem to change. Do yours vary? I also have one stubbornly swollen lymph node on my neck, for years now. I have asked to be checked for ovarian cancer, leukemia, and lymphoma before and have had doctors literally laugh in my face. My only blood work abnormality right now is very high eosinophils, which no one can figure out so far.

I'm definitely with you in not wanting to see another doctor ever again! I've given them hundreds of chances to help, and still no one has....

On the bright side, since your still treating- these levels have a chance to improve.

I only had low lymphocytes in the WBC count. And low in the sub-classes that it derives from (T,s B,s and immunoglobulins. They say low levels of these are sometimes seen in autoimmune (which I have, but some improved). Low globulin protien too.

Bottom line- lyme can damage your immune system, prob more the longer one had it. Going to the immunologist again soon. Autoimmune is hard to reverse, despite what some people assume (and they usually dont have it). There are genes for this too, and I have those as well, guess the switch flipped some time ago. One parent had similar stuff too.

When I’m “on” the abx - my wbc count goes down out of range.
Usually around 3.6 to 3.9

When I’m on the “off” week they go up to low 4’s

I was told to take leucovorin (pharma folinic acid) for that.
I don’t see how that will help..

Edit: google says folinic acid can help increase wbc count.