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My TSH is 27!

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Posted 5/19/2022 2:54 PM (GMT 0)
My TSH has bloomed to 27 after being 17 two weeks ago. The range is 0.5 to 4.5. What is going on? I am on my Synthroid of 50 mcg. Previously it was 9, then I started my Synthroid then it went to 3 and 0.01 after tht. SO I thought that the Synthroid was working. Now checking again it has skyrocketed. What should I do now? My antibodies , free t3 and free t4 are all in normal range. Is this lyme or something else?
Posted 5/19/2022 3:21 PM (GMT 0)
all intracellular infections including Lyme and bart can trigger auto-immunity

the thyroid gland is particularly sensitive and often the first auto-immune condition to pop up.

27 is indeed high for TSH - ideally it should be around 1.

one of the issues with auto-immunity is it can be unstable - especially in the early stages- so rather than steady state of low thyroid hormones you can end up with fluctuating high and low levels - levels can be high due to tissues damage in the thyroid gland releasing thyroid hormones - then i would expect T3 and T4 to go high and TSH to go low - but there may be a lag - so these things can be out of synch when you take the blood test snapshot.

this can be more likely during an inflammatory flare of illness or treatment - so that could be interacting and causing the odd results

one other possible explanation of a TSH of 27 but with normal T3 and T4 could be due to blocking effects of Reverse T3 - something the body makes more of when there is lots of inflammation
so it may well be worth testing that to see if its part of the picture.

ultimately its the T3 that your body uses - so its the levels of that that matter most - and if that is somewhere near middle or the range - the TSH result could just be a bit of an anomaly

as you are probably gathering - thyroid health is a pretty complex topic with quite a few ins and outs to get your head around - so just go step by step and work your way through it - there are a few knowledgeable people here who will help

i found this guy one of the most useful for explaining what could be going on - has lots of fre resources on his "start here" page
https://www.restartmed.com/start-here/
Posted 5/19/2022 4:21 PM (GMT 0)
Since the frees are the hormones your cells use (and those are in range), do you feel better?

TSH is only a signal from the pituitary gland, and............have you had your pituitary checked?
Posted 5/19/2022 4:44 PM (GMT 0)
I never noticed a difference with thyroid medication. What would be the treatment for this if my tsh is high but everything else is normal. What could be wrong with my pituitary? How do I get tsh back in normal levels?
Posted 5/19/2022 5:20 PM (GMT 0)

bro123 said...
I never noticed a difference with thyroid medication. What would be the treatment for this if my tsh is high but everything else is normal. What could be wrong with my pituitary? How do I get tsh back in normal levels?

First - dont panic....because your frees are fine and you feel ok.

Note:.. I've had all of this and more. It corrected.

There is no treatment drug for this oddity.

***Time and understanding how that happened is the treatment.*** Usually resolves on its own. TSH reading are why you cannot use this only to treat thyroid hormone levels. Experienced Drs know this, but just as many do not.

1)TSH lags and can take a while to reflect the state of your "frees". Frees are more important.

2)Stress can also mess up your TSH; Stress to you body is not just physical but also biological chemical changes (like infection)

3)Reverse T3 (another test) can also screw up the TSH but usually accompanies very high free T3 (that is not absorbing in cells). This is also triggered by stress.

4)The pituitary gland is the master hormone gland and can go goofy if there is a nodule on it, that is why Drs test it if the TSH and Frees dont "match up" after a while. This is and mri image. A goofy pituitary will also mess up other hormone signals, so first they they test other hormone signal levels like adrenal ATCH (lab test)(might be wrong acronym). NOTE: Ive had nodules on two endo glands and im doing well, one dissolved in time.
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