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Neurological Babesiosis Study

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Posted 6/3/2023 2:28 PM (GMT 0)
Peter Krause and fellow Yale colleagues just released a new retrospective on neuro-babs. To me that is significant even if it is a retrospective limited to acute cases.

Cannot recall how to link to the study. Sorry. But appears it's a neuro-babs acknowledgement from one of the key 2006 guidelines authors - so packs some serious implications imo.,
Posted 6/3/2023 4:34 PM (GMT 0)
probably this one

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc10202888/

i was surprised to find chronic malaria is a common finding in school children in sub Saharan Africa - where it presents as failure to thrive and learning and developmental issues

its thought this is a good model for chronic babesiosis - as they both sequester organisms in the venules and microvasculature and cause changes to blood flow and inflammation which drive teh symptoms
Dr Lindner writes about the similarities in his recent ILADS presentation

in that paper they describe the symptoms as
"The most frequent symptoms were headache, confusion/delirium, and impaired consciousness."

you can see how reduced blood flow could directly cause all of these

whereas when we look at neurologic issues to do with bartonella - we typically see all of those (probably by the same mechanisms) but also many more symptoms that seem to be nerve damage type symptoms like neuropathies, pain syndromes, autonomic nervous system dysfunction, psychosis etc
Posted 6/3/2023 4:51 PM (GMT 0)
Yes, Garzie, that's the one. Thank you.

As you know, the ILADS community has discussed babesiosis as a parasite that can impact us systemically, across multiple organs, for years. It's not just a cousin to malaria in DNA or impact. It doesn't just cause night sweats and shortness of breath etc. It can and does levy a lot more damage and disability.

But this is from an IDSA guy, yes?. This has to do with cognition and brain matters, Wish they'd looked at cases beyond acute parameters. But this is a step in the right direction, just as IDSA types admitting that Lyme doesn't have to be limited to a bullseye rash and arthritis was a step in the right direction.
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