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Sida Acuta dosage conversion

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Posted 10/15/2023 2:52 AM (GMT 0)
Sorry if this is too niche of a question, but:

There is no information on the internet or in Stephen Buhner's Lyme books about how much Sida Acuta one might need if one had the herb in dried form, not powdered.

I'm seeing tincture info and powdered herb info.

Also, it's hard for me to believe that he had any prior experience with steeping the powdered herb before writing that that's what we should do in the book, because steeping the powdered herb turns the liquid into a mucus-like substance which is very difficult to work with.

Anyway, it seems much more reasonable to me to steep the cut and dried material, so one could strain it, but I'm surprised I see absolutely no information about perhaps the *weight* of the dried herb.

Anyone have a clue?
Posted 10/15/2023 9:37 AM (GMT 0)
Hot water decoctions are listed in traditional uses.

There may be some dosing information in some of the references given here.

https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/sida-acuta#:~:text=Different%20parts%20of%20Sida%20acuta,Coee%20and%20Anderson%2C%201996a).

Otherwise as a v rough rule of thumb hot water decoctions typically yield extraction of max 25% of active compounds (much less if cut and dried vs powdered form)
Whereas high alcohol content tinctures might extract 75%

So you can use that to work back from the tincture dose (relate active constituents of each) as a start point.

Unfortunately the larger the particle size the poorer the extraction.
So while mucin may be less with cut herb - so will active compounds.

On the other hand Alcoholic extractions of sida above 50% alcohol have no mucin issues.

Alcohol is also a better solvent for alkaloids( many of the active plant compounds in sida like cryptolepine) in general.

Ph is slso important for water decoctions as alkaloids are not so soluble in neutral or alkali water - but have much better solubility in acidified water. Eg adding lemon juice or apple cider vinegar.

Alternately you can just consume the herb eg powdered, in juice or in capsules, or as a paste in soft tablets that can be swallowed.
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