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I have  suffered migraines since I was 7 yrs. old.  I have had success with Zomig.  but over the last 6-8 months the frquency has been increasing with the weather changes we have had.  I have always been affected by the weather.  I have many drug allergies and do not tolerate drugs well.  I am currently at 50 mg. of topomax and am having difficulty with side effects.  Any ideas out there? 

I am on topamax 200mg daily, I had to build my way up to the dose. The side effects that I had are tingling in hands fingers numbness in face especially around mouth and nose,and weight loss i'd say about 25 pounds. As for the crying spells that others mentioned I had none of that it actually helped me with my depression and I was able to come off of prozac. I have been on it for over 6 months now and the tingling has gone away and the weightloss has platued...my my headaches have gone from 5-6 a week to 2 maybe 3 a week so it was made a great big difference in my life!! I take it a night before I go to bed.

  I am also in transition between meds for acute headaches, I am supossed to be taking DHE injections but that are horrible so I put myself back on the Zomig nasal spray which doesn't take the headache away completely but gets me to a point were I can function. I just haven't made the appt with my Dr to get something else new..

I hope some of this info is helpfull..

Jess