I keep the end together until it is pointing down into the toilet and let it empty via gravity...then I just use a "wad" of tp and wipe the edges first, then get the first two sections of the inside...roll up and seal the velcro. Some times I do get stuff on the velcro part but water usually takes care of it.
The first time I empty a new pouch, the ends can stick together, but after that first one it usually goes easily.