Here's an article from a Daily Medical News service I subscribe to about
change in lifestyle and its effect on prostate cancer.
Study suggests lifestyle changes may alter genes in men with early stage prostate cancer.
Reuters (6/17, Dunham) reports, "Comprehensive lifestyle changes, including a better diet and more exercise can lead,...to swift and dramatic changes at the genetic level," according to a study published in the Proceedings of the National Academy of Sciences. Researchers followed "30 men with low-risk prostate cancer who decided against conventional medical treatment such as surgery and radiation, or hormone therapy." The patients had "three months of major lifestyle changes, including eating a diet rich in fruits, vegetables, whole grains, legumes, and soy products, moderate exercise such as walking for half an hour a day, and an hour of daily stress management methods such as meditation."
According to U.S. News & World Report (6/16, Healy), "Associated changes in gene behavior after three months of the intervention program were based on analyzing normal prostate tissue from the before-treatment and after-treatment biopsies for levels of RNA, the molecules that translate the DNA blueprints into action." The researchers found that "[e]xpression was beneficially changed in over 500 different genes."
The U.K.'s Telegraph (6/17, Highfield) notes that overall, about "50 disease preventing genes were upregulated, or turned on, and certain disease-promoting genes, including genes involved in prostate cancer and breast cancer, were downregulated, or turned off." This research was conducted by "Dr. Dean Ornish, founder and president of the non-profit Preventive Medicine Research Institute and clinical professor of medicine at the University of California, San Francisco." He was "[i]nspired by studies that show prostate cancer is rarer in parts of the world where people eat a predominantly low-fat plant-based diet, [and] he devised a vegan diet for patients, along with exercise." Results of this study "complement earlier work that showed that, after a year, PSA levels (a protein linked with prostate cancer) decreased in men in the group who made comprehensive lifestyle changes but increased in the comparison group."
WebMD (6/16, DeNoon) quoted Dr. Ornish as saying, "People say, 'Oh, it is all in my genes, what can I do?' That's what I call genetic nihilism." He added that the diet followed in this study "may be an antidote to that," and "[g]enes may be our predisposition, but they are not our fate."