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University of Michigan study shows hope in treatment of aggressive form of prostate cancer

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Posted 3/2/2011 8:26 PM (GMT 0)
Maybe this offers some hope to those here with more aggressive cancer: 

http://www.annarbor.com/health/specific-therapies-for-aggressive-form-of-prostate-cancer-shrink-tumors-up-to-74-percent-in-mice/ .

In the new study, mice with the aggressive form of cancer were treated with an antibody for SPINK1.

“Your body makes antibodies in response to infections or foreign proteins,” Tomlins said. “It’s the basis for immunity. By injecting proteins (like SPINK1) into a mouse, the mouse will make an antibody for that protein.”

The antibody, which has not yet been developed for human use, shrunk the tumors in mice by 60 percent. When researchers injected mice with an already FDA-approved drug called cetuximab, tumors were reduced by 40 percent. When the SPINK1 antibody and cetuximab were injected together, the tumors shrunk by 74 percent. These results were only true for tumors that expressed the SPINK1 gene.

Posted 3/2/2011 10:23 PM (GMT 0)

Hi MichGuy,

With all the successful treatments they have found for mice, it is a wonder that any mice, with cancer, are left to experiment on :-) . Now if they could only find something that would works on us humans.

Thanks for your interesting post.

All the best to you.

Mag

Posted 3/3/2011 1:19 AM (GMT 0)
Yeah Mag, if only!  I didn't dare mention the experiments they are doing with mice and pomegranate juice... nono

Best to you, too!

MichGuy

Posted 3/3/2011 4:47 PM (GMT 0)
What's really sad is that it seems to take at least 10 years to move from mice to humans...I just don't understand it..If the new treatment passes some basic toxicity tests, what's the problem with testing it on terminal cancer patients who volunteer to be treated??
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