Using Trimix

Last night I used the Trimix inj. sample that my Urologist supplied.  This was my 1st self injection.  My Dr. gave me the 1st one in his office which was .5cc (I don't know the percentages of the drugs in this injection).  I achieved a erection that seemed about 90-95% of my pre Prostatectomy size and it last about 75 min.  The Trimix inj. he sent home with me was .75cc

After I self injected, I got an erection in 5 min. and made love to my wife.  We were engaged for approx. 20-25 min. and I could tell that I wasn't going to have an orgasm but at least she did.  I guess my nerves are still haywire.  It was still great and the intimacy was so good to get back.

Afterwards, my erection began to sting and was painful.  2 hrs. later, I took 2 Sufafeds and iced down.  The erection finally subsided after 3.5 hrs.  I was really scared that I would have to go to the ER.  

I think that the 7.5cc was too much and maybe the strength was too high.  I'm seeing my Dr. in 10 days and I'll discuss this with him and either try a smaller dose and/or lower strength.  I'll also request a 31 guage 7/16 needle vs. the 1/2 in. 30 guage that he supplied.  I have a slight bruising at the inj. site.

Have any of you experienced these problems and did you all have orgasms the 1st time?  What has been your experience with BiMix vs. Trimix?

I have a little story to share that may provide hope to some; though likely only a small minority. At least it may speak to single guys if there are no swingers out there. The story is dedicated to Biker90.

I happen to be blessed with one very amazing wife. Before my Dx, she and I had been dabbling with the idea of swinging. I was ready to jump in; she wasn't quite there. We had met another couple years before for that purpose, but just became regular friends instead. Then came the PCa Dx and all the emotion with it. One day, with weeks to go before the scheduled surgery, she came to me and said she was ready if I still wanted to. I said hell yeah, and called our friends. Two weeks before surgery we all four had the night of our lives. Two solid hours worth before I was spent. 

Then came the life altering surgery, pain and complete ED. After 8 weeks I got Trimix and was finally able to penetrate my beautiful, hugely sexy wife again. Once we discovered how well that works, (at least half the time - very inconsistent results), she put me to another challenge, as she had been throughout my Dx and recovery. In mid September She said we are going to spend another night with our friends, so you had better get yourself in top shape. We had a date for Oct 23rd! Wow; I was working out in the gym like never before, doing my Kegels like never before, and "practicing" sex like never before. Several days before the big event my wife and I decided to have sex that evening, and I gave myself the typical Trimix dose. Failure; nothing happened. I had been getting zero results about half the time. I posted here and elsewhere a plea for help the next day. One day before the event, last Friday, a member of HealingWell, named Biker90, came through for me with just the tip I needed which I hoped would ensure the dick I was going to need. Last Saturday night was the most amazing night of sex I have ever had in my life. Our friends have no idea I have cancer; yet. They have no idea I used Trimix. Over the course of a long night of dinner, conversation and eventually sex, the 4 of us consumed 8 bottles of fine wine. Then the four of us had FOUR hours of solid sex together like never before. Naturally the other guy would go soft after he would have an orgasm, so I was relied upon to keep both ladies happy until he got hard again. FOUR hours! I haven't done that since I was in my 30's. Of course I had to fake NOT having an orgasm, a feat for which having no prostate comes in very handy. The other lady kept asking my wife; is he ever going to cum? In actuality I came several times. Finally after four hours I began to soften. Never did I have pain; always before when my erection lasted more than an hour after sex I had a lot of pain. Not this time for some reason. It was beautiful, just like sex before surgery, (but a little less mess).

Anyway, there is not only life after RP, but amazing, wild life if desired, even for you swingers and single guys. And there are great guys out there in the blogosphere ready to help us newbies every step of the way. 

Thanks a hundred million, Biker90.

I love my wife; I love my life.

PS. I start ADT tomorrow.

Sigh....
Jeff (the one with the leaky winkie)

Hi Nopro,

There is not a big diameter diff between 30, 31 or 33, but there is a big diff in flexibility, 30 bends pretty easy and I stayed with that and have no issues. I tried 31 gauge and the only diff was it bent very easy , to easy when trying to fill it. It felt the same as the 30 when injecting

Try to get a brand that works with an auto-injector. I use the BD inject-ease. It makes the process much easier, safer and less chance of getting the willies from seeing a needle enter your skin as you never see the tip at all. Click and your in, perfect placement every time

The Inject-ease also has depth adapter rings so you can tailor the depth to exactly what you need. here is a link as an example

www.phoenix5.org/sexaids/injections/automanny.html

I must correct my last post.  They were 30 guage 1/2 inch needles not 1 inch.

JStars

Thanks for the input.  I thought that all the nerves were interrelated.  The lack of semen after prostatectomy may be hindering my progress toward achieving orgasm, at least mentally.  That release always was so satisfying.

How come you haven't tried Trimix?  I think I'll be fine with it once I get the proper dosage.  The injection with the BD Inject Ease, 30 guage, and 3/8 in. depth (with 1/4 inch spacer) made it a painless process.  

musicmoney, welcome to the Forum. You sure have a strange- to us- ration going there. Most here use a 30mg/1mg/20mcg (or 10mcg) Trimix formula. Yours, if correctly typed seems to be 5 times as strong in the normal stuff and 7 times as strong in the alprostadil end, which provides much of the punch of the drugs. Is that right? At the 40 units level, that seems an enormous amount to use, especially to just get 'fairly well' results. I'd be interested in what exactly is on the bottle itself?

As to changes, I see you mention massage before and after, but are you familiar with our almost patented, tried and mostly true pump and prick method of pumping the penis up about 30% using a ring or some kind of constriction top hold the blood in, then injecting and gently massaging for 3 minutes before releasing the ring and allowing the blood (and the drugs) to run out of the penis? If not, thats a great technique to get maximum adsorption of the drugs into the penis..

Hey NoPro,

You asked me a while back ...

How come you haven't tried Trimix? I think I'll be fine with it once I get the proper dosage. The injection with the BD Inject Ease, 30 guage, and 3/8 in. depth (with 1/4 inch spacer) made it a painless process. said...

Well, after reading about Trimix Freeze Dried on another thread,Light Dawned and I said to myself - "Hey, I've got a whole BOX of Freeze Dried Trimix from Amer Pharma Solutions!".
That made a strength of about 10mcgPap, 3mcgPhen,50mcgPGE-1 in 30ml -- A bit strong on the PGE and very weak on the other two ( yeah those are really mcg not mg levels per ml). But using .20 ml at that strength is working very nice with 2+ hr erections and good chubbies long after that -- and ZERO ache.

So one long time pumper is sold on injections. Also at a calculated 60 cents per injection (very conservative 100 shots per bottle including trimix($30), water($5), needles($20), alcohol wipe($5) costs) that is right up there with ADC double pills price per (which don't work anyways).

So things are looking up here .. yep.

J

Post Edited (JStars) : 3/6/2011 4:35:10 AM (GMT-7)

Hi Island Guy

I started my TRIMIX injections from my URO last week and the first shot is his office was .3ml and I got to about 60% erection. He told me to try at home with a .4ml and then go up .05ml until I find the correct dose that gets an erection strong enough to use for penetration and lasts no more than an hour and a half. He didn't give me a high limit. Saturday I injected the .4ml dose and got to maybe 70% while standing but as soon as I joined my wife in bed it went down some and was worthless. I will try a .45ml dose later this week and see how that goes. Another in here suggested I look into a penis constriction ring to keep the blood in while I am not standing. Living in Alabama all the adult toy stores have been run out of business so my URO suggested a Hardware store bought rubber "O" as long as isn't too tight for the blood loss problem which he thinks is from my "spared" nerves still not over the RALP trauma. I shall see later this week. 

Terry the Water Guy

.o2 to .03 of trimix is good for me

Murple,

You said it stayed in the fridge for "a while" -- how long is that? Trimix loses some of its strength after a few months in the fridge. I'm a bit confused about how much volume you are injecting. 0.01 ml is one "unit" on an insulin syringe (like you and I are using) and my syringes hold 50 units. I'm not sure I could reliably inject that little -- it would represent something like a 1mm motion of the plunger. Did you mean 0.1 ml (10 units?) I've never heard of anyone injecting 1 unit of anything.

I have an autoinjector. I used it for a while but the positioning is a bit problematical sometimes. It usually works better to man up and jab yourself manually. I use a 30 gauge needle (you may have to ask) and it seems more comfortable. Be sure to avoid injecting at the 12 o'clock position (right on top) and don't go past half way down the side. Stick to 1-3 O'clock on the one side and 9-11 O'clock on the other.

Don't get discouraged. It takes a while to zero in sometimes. As I understand it your doctor would be OK with you going up a bit (gradually and carefully, trying each dose twice) until you find what works.

Welcome to the forum, by the way. Hope we can help out.

Murple,

Adrenaline tends to counteract the effect of the trimix (so you need a larger dosage). Every guy is freaked out injecting in the doctor's office so 30 units is your so-nervous-my-head-may-explode dosage. You may have let that first failure throw you and become anxious. That'll make your dosage required go up.

Do try to relax. You will find a dose that works reliably. Ask your doctor about how fast to increase your dose. Often going up by 20% is about right. 120 percent of 10 is 12. 120 percent of 12 is 15 (you round up to the next unit).

Good luck. It will work for you.

Thanks again Peter.
Spoke to the Doc today. He wants me to go to the original .3 dose and try that.

I like your math better and from what I've read on the site small changes can make big differences. I'm going with the 20% increment method.

txrick,
Absolutely no expert here but for me the pump enlarged things but not enough for penetration. Your experience may be different.

While I was complaining above about the reactions or lack there of I have confidence it will work once I get worked out. In my experience the thought of the injection is 1000 times worse than the actual injection. With the auto injector there was zero pain. Self injecting it was just a small pinch.

Again I'm new to this so.....don't take my word for anything.

Post Edited (Murple) : 1/21/2014 4:16:32 PM (GMT-7)