psa tripled in three month

leeanglo,

For tiredness, you need to get on a good exercise program: cardio + weight/resistance training. The resistance training will help build back your muscles you are losing through ADT.  More muscles will help mitigate the fatigue.

For erections, there is the pump or injections. I guess some ADT guys can do ok with oral meds but the pump or trimix is only thing that works for me.

I have mentioned before that estradiol patches or DES, estradiol gels or emcyt and likely either tamoxifen or relaxofene added to your LHRH drug (Lupron etc.), will help cancel the side effects of the LHRH drug and also assist your bone density and fight hrpca at the same time, and thus improve your lowering into psa numbers. I highly suggest you find a doc to let you try it and see for yourself via psa testings and how your feel, the estrogenics work quickly on your system, I had lupron still in me (active) and with days the DES canceled the side effects and tested with 14 days big drop in psa and in my case stabilized psa for years thereafter.  I have a link to the 2003 Journal of Urology article on findings about DES, amazing they published it in there Journal with alot of researchers findings.

Now if you take these estrogenics later in the game, vs. more early on they may not work as well or as long in patients, as seen in some others.  You should be hopefully looking at all your possible options, see www.hrpca.org  and  look into  newletters on line pdf files at www.paactusa.org  (free).

Just trying to give ideas and maybe helpful on this for yourself or others, you decide of course, but you also posed the question and so got a response.

Good hunting in this.

Post Edited (zufus) : 2/18/2012 10:30:08 AM (GMT-7)

I used DES 1-mg and worked wonderfully on canceling hot flushes and other effects and worked way better than ADT3 drugs. I don't know on the patches, as to how much or if with patches it varies alot more on that...I believe we have 1 or 2 guys on this forum using patches w/lupron and helping with the side effects...hope they can tell you something. Mylan square patches are larger, adhere better and may be a better patch, friend of mine switched from Vivelle dot patches because of adhesion issues and stuff.


Other things for hot flushes that do work are: megace, megestrol, cyproterone acetate, soy?, gabapentin, zoloft, effexor (37.5 mg- used by Dr. Yu found very effective).