another strange Trimix experience

My gut reaction is to NOT let it go beyond four hours to avoid permanent damage.

I think the mix is too strong.

You could reduce the volume of the injection or ask the uro for something much weaker.

 

Glad to see your husband is back at it after the last mess. I've had one erection that lasted 6.5 hours because I fell asleep and wasn't aware of it. It isn't fun. I'm still working on what my correct dosage is but so far I've cut my dosage back to 25% from the 25 units the uro used in the office. My next injection will be .06cc or 6 units. The last two erections using 8 units lasted 2.5 hours. I have to have all of the lights on to see the hash marks on the syringe. It doesn't help that I need new glasses.

My uro told me damage starts at six hours. I believe the four hour rule comes to play because you have to get to the ER, you have to be admitted, they have to call the uro on call, the uro on call gets a middle of the night phone call usually around 2:00 am, the uro has to get dressed and drive to the ER, and then finally they can start doing something about the priapism. I doubt there was any damage in five hours. I agree your trimix is a rather hot dose. My compounding pharmacy has two common mixes. The high dose is exactly double the low dose that I use. Here are my dosages:

Papavirine 15 mg
Phentolamine .5 mg
Alprosdtadil 5mcg

Your trimix is
Trimix 27/0 .45/45
papaverine/phentolamine/alpros

You are getting about double the Papavirine and nine times the alprostadil per unit. .1 is still way too much so I would suggest cutting back to .02, .03 or .04. It is you and your husbands call. When you get close to zero it becomes difficult to see the line, and you may have to get a weaker blend. I will only inject if it is before 6:00 pm until I get this figured out. I've had two misfires when shooting my left side because I'm right handed. One was a total dud and the other was a flash in the pan at .08. We got two minutes of sex out the flash in the pan. I was just about to increase my dosages but didn't and the last two injections have both gone a little over two hours which is the reason for further reduction. I figured those two miss fires are the results of not hitting the target and I need more practice.
Good Luck to you and your husband.

Everybody is different in their tolerance to these drugs.
Do you realize that if .05 works for you two love birds that you will get 100 injections out of a 5 cc vial and the stuff will only last three months refrigerated. Despite the fact that I'm still playing around with the dosage, this morning I pre-filled 15 syringes up with .08 cc and put the vial in the freezer. My trimix is already a month old so that leaves only another 8 weeks before it starts to go south. We will probably need 8 weeks to finish up the 15 syringes I prefilled. But at least the vial will last longer. I would rather waste 2 or 3 units out of each syringe than have the whole bottle go bad, I cannot remember what the life span of trimix is frozen but I think it was about double. As soon as we use up the prefilled syringes, I will defrost the trimix for just a couple of days and fill a dozen more syringes. By then I hope to have the dosage figured out. Straight Asprodil gives my penis a real ache. Trimix is tolerable but still isn't enjoyable after an hour so I'm hoping we can get this down to the bare minimum or erection time needed. I would be very happy if I could get it down to 45 minutes which was about how long the first .08 injection lasted. It is really strange how the dosage is a moving target at this point.
Good Luck

Hi Susan, I just want to salute you on your honesty, openness, and above all your ability to discuss a subject many wouldn't be able to with the same naturalness as if you were dealing with an ingrown toe nail.

While this allows others to respond with the same candor, to your's and Michael's benefit, it also allows legions of others to be a little less closed --- if only when dealling with their doctor, or wife, and not necessarily here.

Good on you! And warm cheers to Michael.

Sheldon AKA Sleepless

I have used bimix for almost 5 years.  I have always had "semi" erections after injection that have lasted for five or more hours.  I was very concerned and had several discussions with my urologist.  He told me that "you will know the difference" between a full erection and a partial one.  In my case the partial one begins within an hour or so after injection and continues getting softer for hours after.  It is about 3/4 or less and can be "revived" if we want to. He said not to worry if it is warm and flexible.  Cold and very hard is the call to emergency room.  I have never needed to make that trip.

Your husband will eventually find the right dosage and make life better.

Susan – Michael should be very careful with the dosage given that he’s had two priapism events.   According to Dr. John Mulhall, a highly regarded ED expert, an erection lasting 4 hours (above penetration hardness) is considered a urologic emergency.   Erections lasting longer than this deprive the penis of oxygen which can kill erectile tissue much the same way that a heart attack kills heart muscle.   Men who’ve had several cases of priapism are more likely to no longer respond to pills or injections.   He says 90 minutes should be the maximum.   If it lasts 2 hours you should take 4 regular Sudafed 30 mg tablets in an effort to get it down under penetration hardness.   At 3 hours you should be in contact with your doctor and if it is still at or above penetration hardness at 4 hours – you should be IN the ER.   I agree that his mix may be too strong for him.   I believe the most active ingredient in Trimix is the prostaglandin (alprostadil is a variant).   By way of comparison my Rx is: Papaverine 30mg - Phentolamine 1mg – Prostaglandin 10mcg/ml.   Now I don’t know if Prostaglandin and Alprostadil compare one to one, but my dose is 10 and Michael’s is 45.   Of course, men respond differently to this medication so it’s hard to compare, but at any rate I would definitely talk to the uro about the dose.   However, no matter what dose you settle on, in my opinion, it would be better for him to go low and work his way back up to an ideal dose.   Expect a few flops along the way, but that’s better than going 4+.   And try each step twice before increasing, just to make sure.   Hope this helps – and Good Luck!   Btw, here’s a video of Dr. Mulhall.   He talks about priapism around 14 minutes into the video.   http://www.mskcc.org/multimedia/penile-rehabilitation-after-treatment  

I wonder if penis size has anything to do with the size of the dosage. For example would a guy who is thick require more than a guy smaller?  It stands to reason that a larger penis may require more medication to get the same results as the medication is injected into the tissue not the blood steam as a pill would be.

Thank you all for taking the time to input. I do appreciate it!!

Maybe Im missing something but I thought the purpose for using Trimix was to be able to have sex. So why would you inject in the morning before you off to work if you were not going to have sex.  I inject when the moment is right beteen my wife and I.

Yes the reason for the week off is because I am out of town Sunday's- Friday's. For another few weeks. He could use it alone, but that would make me sad. I want full use of that hard erection!!! Woo hoo!!!! (was that too much info?)

I think itys great Susan's react to Trimix and it sounds like she's very supportive of her husband.

My wife was too. It was so great not having to worry about me getting "up" or staying up, Also she actuallys helps me with the injection. Massaging it in., Thats a turn on for bother of us.