That supplements don't prevent prostate cancer didn't suprise me, but this paragraph really got my attention. It's in relation to so-called over-diagnosis, overtreatment, and overscreening:
The 50-to-one ratio is based on short-term follow-up and "grossly underestimates" the lives likely to be saved by screening over the long term and overestimates the number who are overdiagnosed. "The correct ratio of men diagnosed with PSA testing who are overdiagnosed and overtreated versus men whose lives are saved by treatment long term is more likely to be 10 to one," she said.
That's a much different perspective on these issues than we're used to seeing.