Newly discovered effects of vitamin D on cancer

Rodger,

Thank you for providing this link. I went to the paper and it is nice that PNAS allows the viewing of the full article (which is better than the biggies - Science, Nature, Cell - funny how the rich journals don't allow access - which sucks as the vast majority of research is funded by NIH!).

Anyway, the question I have is how much Vitamin D is needed in a person (this study is in tissue culture and with explants from mice). Can it be in pill form or must it be in foods? Moreover, there is risk of too much Vit. D and that is a rise in blood calcium that can result in kidney stones and calcification of soft tissue.

I guess I am skeptical because recent meta-analysis of vitamin supplementation in pill from suggests the efficacy low and that you must eat the foods. I've been taking vitamin supplements most of my life and the inevitable pCA happened. I know it is no guarantee but we have this illusion we will be ok and then, Wham. These in vitro studies and mutant mouse studies are nice but translation to real therapies are often few and far between.

Still the whole vit D thing is very interesting and encouraging. Does anyone have more information on VD, I mean vitamin D? I'd go sit in the sun right now but it is raining in Philly and I might get melanoma if I did.... LOL (we can't escape this Ca thing!)

Godspeed to all,

Christopher