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1st trimix injection

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Posted 12/5/2013 2:25 AM (GMT 0)
I'm new to the forum, I had radical prostate removal may 2013, my 1st psa test was 0.3, I just completed 38 radiation treatments last week; I'll have another psa reading in feb.2004,,,,,I just got my 1st order of trimix today; I want to do it in a few days and want to know what dose is good to start with? I feel confident enough to do my 1st dose at home not the dr.'s office..thank you.
Posted 12/5/2013 3:00 AM (GMT 0)
My advice is to read quite a number of posts concerning trimix dosages both here on HW and also on Franktalk.org. Start with a low dose and gradually work up from there. Be careful of the 4 hour rule, and if the tri-mix hurts like hell, ask the doc about using bi-mix instead.
Posted 12/5/2013 3:51 AM (GMT 0)
Did your doctor tell you it was OK to do your first jab at home? I did mine at home but I wasn't supposed to. My urologist says I was ignoring the instruction sheet he gave me with the prescription. I claim he was in a hurry and chatting with my wife and I didn't get the instructions. I figured it out for myself with some help from the guys on the forum.

Probably the reason you don't know the dose is because he is expecting to give it to you when you bring your trimix to his office for your first shot. If you read us the concentrations of the three drugs that are written on your bottle we can tell you how much we used as a starter dose. Of course, we will just be reminiscing -- the instructions for your first shot ought to come from your doctor -- there is no medical advice to be had here.

Call your doctor to make sure.
Posted 12/5/2013 5:37 AM (GMT 0)
shutterbug1024,

I did my first injection at home. I started low at 3 units (very small amount), and it worked about 30%, then i increased by 2 units till i reached 15 units or so.
At 15 units i had 80% erection which was good, but the erection remained for 3 hours, so i back off the units.

The prescription and compounding pharmacy can provide differing formula strengths, so that's another reason to start at low units, in case yours is high octane.

I am pain sensitive to the alprostadil (one of the 3 ingredients). So, now i use Bimix, which are the remaining 2 ingredients.

Wally
Posted 12/5/2013 8:35 AM (GMT 0)
My uro made me sign a protocol (required by the ins. co.) that stated I did the first injection in his office under supervision. Because of how my insurance is constructed, if I did it at home after that, and had any issues, they would not be covered, at all.

Someone else in the company had severe issues after going it alone, and paid through the "nose" for retail costs of ER and hospitalization.

Follow the docs instructions.
Posted 12/5/2013 2:43 PM (GMT 0)
I had my first injection at home week or so ago. My doctor had told me to start at 0.25 then move up to 0.50. From what I read here I thought that was a bit much, I started at 0.10 and it was about 90% for 45 minutes. I'm gonna move it up to .11, then .12 till I get closer to 100% but stop when I go over 90 minutes. Truth is 20 minutes is more than adequate for my plans. Lol

I do think if I had followed UROs suggestion to start at 0.25 I would have ended up at ER, instead we had a nice evening with no VED and band!
Posted 12/5/2013 5:39 PM (GMT 0)
After reading posts on this forum, it is clear to me that some uro's have no clue on how to help clients with trimix and give out improper information....mine included... !!!

This site gives out the best information and cautions....read, read, read.

Happy Holiday's everyone !!!

Cheers !!!

Curt
Posted 12/6/2013 4:36 AM (GMT 0)
Same here; Told my urologist I would like to try Trimix. He wrote me a script gave me a brochure of instructions, sent me home. script told me to inject .50 units but after reading some of the post I started with .10, the ended up with .13 that works. You are absolutely correct, some of the urologist know very little about ED and how to treat it. I get most of my information from this forum and the internet. Another note, I bought anInject Ease injector from Amazon, it makes the process a little easier.
Posted 12/6/2013 5:25 PM (GMT 0)
Shutterbug -- Welcome to Healing Well, sorry you have reason to be here, but glad you found us.

I'll echo what others have said: Start low & go slow. Be patient. It's a good idea to try each dose more than once before moving up.

The right dose depends on each individual, their sensitivity to the medicine, and the strength of the blend of medicine in their Trimix. Trimix is a custom mix of 3 medicines according to your doctor's prescription.

My Rx is: Papaverine 30mg - Phentolamine 1mg – Prostaglandin 10mcg/ml.
I started at 0.05 cc and gradually and carefully worked my way up to 0.20 cc, which was the right amount for me. I was required to have my 1st & 2nd injections at my doctor's office; the first he administered, the second I gave to myself under his supervision.

Dr. Mulhall says, for penile rehab, you need to have erections that are penetration hardness (60%) or better for 10 to 15 minutes 2 to 3 times a week. This will maximize your ability to recover your erections back to what they were prior to surgery. He also says that your maximum duration at penetration hardness, should be no more than 90 minutes.

Realize also that ED recovery takes time, usually around 18 to 24 months.

Good luck with all aspects of your recovery -- Tigerfan
Posted 12/7/2013 3:36 PM (GMT 0)
Update

Moved up to 0.11 from 0.10 previously. Difficult to believe such a small increase made such a difference. At 0.10 I was nearly 90% and lasted 45 minutes. With the small increase still around 90%, but tried drinking 4 cups of strong coffee afterwards, than at 2 hour mark took the sudafed. All told it lasted 2.5 hours, I was getting a little worried. I think I'll be sticking with the 0.10 dose.
Posted 12/11/2013 1:40 PM (GMT 0)
Gentlemen,
as a follow up to your wonderful input: I went to my Dr. for my 1st injection yesturday; he gave me 20 (a number on the syringe) I drove home with a semi woody; I hopped in be with the Mrs. long story short ,I couldn't quite do the deed; I was about 75%......we tried couldn't quite do it, waited another 15 min and it seemed harder, tried again.......not quite :( we were pretty bummed......so I'm thinking 25 would do it....I had the injection at 4:00 and it completely ended at 6:00.....all in all I was dissapointed because it felt uncomfortable and slightly painful feeling. I don't know; I'm gonna give it a rest and try again next week......my wife thinks its because I was anxious about having the injection at the docs office and just stressed out.......she's right I was a little stressed over this whole thing plus I'm generally a hyper person too.......should I try 25 or 30; on the bottle of mix its says trimix 30 and then two other chemicals at 3 each? "the things we do for love".....
Posted 12/11/2013 2:58 PM (GMT 0)
Try it again at the same dose first. Then if you need more, go up 5 units at a time. The discomfort may be a pain reaction to the alprostadil. Some guys find that it gets better -- or they get used to it -- but if it persists and is troublesome, talk to your doctor about bimix. I get an ache from the alprostadil but it isn't bad enough to discourage me.

When you try the next time bear in mind that you are experimenting looking for the right dose and if it can't be made to work that isn't a failure -- its a datapoint. Eventually it will work for you. Don't get too frustrated while you are hunting for that magic dose.

The syringes we use are insulin syringes and they are graduated in "units" of 100 units per ml. So your 20 units is 0.2 ml.
Posted 12/11/2013 9:52 PM (GMT 0)
And just so you know: 20 units = 0.20 ml = 0.20 cc
Posted 12/25/2013 2:40 AM (GMT 0)
Gentleman,
I tried Trimix for the second time tonite; I tried the same amount (20) this time it worked pretty good....I was able to do the deed with no pain or ache at all; however it did ache when it was coming down; it was the first time I did it since my operation last May 15th, needless to say we were both pretty happy and relieved...it took 2 hours before it we away.....do you think if I try 15 next time it would work? No sense in having a woody for 2 hours if I only need it for 30 min-60min.....this was the first time I injected it myself....it really wasn't that bad at all; I just read the instruction twice and did it.....when my Dr. did it at the office it 'burned' a little........I didn't get that feeling at all when I did it; I didn't feel a thing and first thought it wasn't going to work but lo and behold; it turned out to be a nice Christmas gift to both of us! Thanks for the guidance and suggestions to all ......
Posted 12/25/2013 2:49 AM (GMT 0)
If you have a needle with detailed enough markings, I would come down by .01 ml each time. For me the difference between .10 and .13 is not useful and ER trip, so small changes can make a lot of difference.
Posted 12/27/2013 6:21 AM (GMT 0)
if you got 2 hours of wood, I would cut it by 3 units. I would rather have a missfire than a trip to the ER. Keep regular sudafed on hand and take four at the two hour mark. Make sure it is regular sudafed. You don't want time release sudafed.
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