Unless you have a very high end insurance policy, I doubt they will pay for any genetic/metabolomic tests. The genetic tests are expensive. They give probabilities of aggressiveness, not assurance.
My opinion is that if money is no object, they may (or may not) be useful. They will rarely give a definitive answer because extreme values are rare. For me, it's a lot of money (since I have very little) to spend on a probabilistic estimate. I think the best use may be for cases where there is some reason to question the aggressiveness of the cancer, say a "low risk" case where there is a significant amount of Gleason 3+3 and PSA has been rising. By contrast, your husband is "very low risk" - the amount of cancer found - 7% of one core - is considered to be "insignificant." Any reputable Active Surveillance protocol will tell him if the PC is progressing -- most PC never does. A repeat biopsy, perhaps with image guidance or a saturation biopsy, will provide assurance that nothing was missed. If I had to spend money, I would spend it on image guidance for a repeat biopsy after a year (mpMRI or CDUS with an excellent radiologist). Meanwhile, I'd be taking Avodart or Proscar.
To clear up some confusion (or add to it) there are different tests with similar names or that do similar things:
Prostarix - There are two tests with this name.
One, marketed by Bostwick/Metabolon is a urine test after prostate massage, used to determine whether to do a repeat biopsy after a negative biopsy - this would not apply to you because you already have a positive biopsy.
The other is done on the biopsy slides. Bostwick also markets Prostyvision, a test of two genetic markers sometimes associated with aggressive PC (cost $1,100).
Prolaris - From Myriad Genetics costs $3,400. It looks at the RNA associated with 46 different genes that become active when the cancer is rapidly dividing. It can give one the probability that one has one of the more aggressive cancer types.
Here's their website.Oncotype Dx - From Genomic Health costs $4,175. It uses 17 genes to come up with a score that correlates with PC aggressiveness.
Here's their website.- Allen