I'm still standing (yeah-yeah-yeah)-UnTx results improved too

Been fighting the PCa dragon for 12+ years now with lousy prognosis from day one and high risk stats that were very scary to start with and included the ER urinary blockage issue from PCa leading to my diagnosis in 2002. Done a blank load of drug therapies over the years and tried a few things on my own combos and trial because I can. (2002 stats psa 46.6 gleason scores 7,8,9's (2 sets) all 12/12/ biopsies 80-95% cancer, ct and bone scan found clear at that time).

I have had high UnTx urine test for bone breakdown, used in monitoring mets happening and it is happening, been radiated now 3 times on spine and once on femur in the last 15 months (such fun). Well this test was high in Feb. at like 243 level and just now found normal at 59 (normal is 21-83). Nice to see this result while still with mets and psa still at 14.22 (to high).

So, since I got Prolia shot last month is that the cause for the big drop or was it the radiations from the last 2 months or so, or is it both. Been on Xtandi for about 45 days+ or so and figure it is not just from that. Anybody have any thoughts or similar results from Prolia (Denosumab)????? Cannot say I notice side effects from Prolia which is good to know. Thought I would share this, maybe it is no so common to see UnTx drop so fast, not sure as I have no info or experience to fall back on.

I like that Jim, I should send you a check in the mail (LOL), we know this dragon is a sob and plays unfairly.....I don't mind playing unfairly against it and the system (as you know). My femur survived a possible fracture and so far same for spine issues thus far radiated. Actually doing some work around here and cleaning out the pole barn and mowing the 4 acres, etc. Wasn't sure I could even handle that stuff just a few weeks/months ago. I was wondering if it were all downhill and fast, so far it is variable. That I can feel a lot better and positive about......

Thanks Steve I have been waiting for a bonus most of life (LOL), usually waiting for it in the form of a large check. Money cannot buy health of course, might ease some pain or hire some top guns though....

Great to hear from you Zufus...

I usually get the bone specific alkaline phostaphase to also monitor bone mets...not sure if I know what your blood test that you referenced is.

I've had xgeva monthly a few years ago and have it every 6 months as maintenance now....so a little familiar with denosumab (xgeva)..

Zufus, you ole dog...you've been on my mind and I was wondering what you were up to! Sounds like you've been busy kicking the crap out of PCa. Keep it up and never, ever give up. We love you and we miss you here. Keep riding high and don't let the beast win!!

Sending you a ton of hugs from The Empire State.

Your Pca journey has been an inspiration to me

Paul

thanks for checking in with some good news. been wondering and worrying a little about you tho I figured you were probably okay

ed

Zufus, what you have accomplished in your war against the dragon is amazing. Keep winning one battle at a time and hopefully you will win the war.

Bob,
Good to hear from you. Keep up the good fight.
JT