Posted 12/23/2014 3:36 AM (GMT 0)
I am trying to get a handle on PSA behavior after salvage radiation therapy.
Halfway through a 6-week course of radiation therapy my PSA dropped from 0.3 to 0.2. This was encouraging because it seemed to indicate that the radiation was on-target and working. However, two months after completion of SRT, my PSA went up again 0.3.
I am thinking the 0.2 reading three weeks into SRT may have been bogus because I can't imagine radiation having such an immediate effect after only three weeks. Anyone have a similar experience?
For those of you who have had SRT following a rise in PSA after an RP, did your PSA bounce up and down before it settled, dropped, or began to rise?
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No symptoms prior to dx.
2013/08 Routine blood test revealed high PSA of 13 (12.7). DRE negative.
2013/11 Transurethral bx revealed cancer in 7 of 21 cores. Staged T1c (DRE negative), Gleason 7.
2013/12 2nd opinion upgraded Gleason 7 to Gleason 8. Scheduled surgery same day.
2014/02 RP with da Vinci robot at Tokyo Medical University Hospital. Catheter removed 8 days later.
2014/03 Post-op path report confirmed Gleason 8 and revealed up to 7 tumors ranging Gleason 6, 7, 8. Seminal vesicles and both pelvic lymph nodes removed and dissected, both vesicles and nodes were negative for any sign of cancer. One margin suspect (pathologist could not decide if it was positive, so it was judged “to close to call.”). Right nerve bundle was taken, left nerve bundle spared. Final staging T1cM0N0.
2014/03 Good recovery from stress-urinary incontinence after 6 weeks, pad free after two months post surgery. ED remains a problem.
2014/08 Hospitalized again to repair large hernia at ventral da Vinci incision above the navel.
2014/09 PSA levels (tested every 60 days since surgery) 0.1, 0.1, 0.1, 0.2, 0.3.
2014/09 Started SRT (EBRT), 30 sessions (6 weeks), 2 gy per session. After third week of SRT, PSA dropped from 0.3 to 0.2. PSA reading after SRT on 27 Oct: 0.2
2014/12/22 Latest PSA: 0.3 (up from 0.2)