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After PSA was reduced from 29 to 0.1: next step?

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Posted 5/11/2015 1:15 AM (GMT 0)
Prior to treatment Gleason of 5+4=9. After three consecutive Lupren shots the PSA went down from 29 to 0.1. Testastorone also went doe from 300 to 1. Suggestions as to next step, please ?
Posted 5/11/2015 1:35 AM (GMT 0)
Welcome to HW.

Let's see, down from 29 to .1.

Party? I'll bring beer. I'd be in celebration mode.

Andrew
Posted 5/11/2015 2:39 AM (GMT 0)
Live your life and hope you have a long remission. Live as if you will.. If and when psa climbs, be sure to have a topnotch urological oncologist from a major medical center, treating you. If you are asking what are the multitude of treatments available after someone goes refractory{ cancer needs not testosterone to spread} there a are books that i think could help with some searching. Also there are a number of members that can help with that information also. Just do not leave yourself out of your treatment loop.

Post Edited (logoslidat) : 5/10/2015 9:54:19 PM (GMT-6)

Posted 5/11/2015 3:34 AM (GMT 0)
foget all about your pc ;your numbers are great, AND enjoy the summer, I take it 3 mo s at a time, when I get my pc treatment, ken
Posted 5/11/2015 4:49 AM (GMT 0)
Any evidence of spread from a bone scan and CT? If not, and if you are young enough or have few co-morbidities, you can attempt to cure it. It's hard to comment without more details of your diagnosis and treatments so far. Add a signature, so people can comment.

- Allen
Posted 5/11/2015 4:57 PM (GMT 0)
Thank you. Age 74. Yes, to bone scan and very detailed multiple prior MRIs--no evidence that cancer has gone outside of prostate. My questions and puzzlement is there a need now to concentrate how to kill / extinguish the remaining cancer cells which according to doctors remains there even if PSA went down to practically zero. when speaking to a doctor specializing to a certain treatment THEY openLY SAY NONE OF THE OTHERS ( competitive approaches) HAVE WORKED SO WELL THAT THEY KILLED THE CANCER CELLS WITHOUT CAUSING A MAJOR PROBLEM SOMEWHERE ELSE.
Posted 5/11/2015 5:31 PM (GMT 0)
Considering your age, you wouldn't want surgery, but you can have radiation. For a GS 9, you will probably do best with a combination of brachytherapy plus external beam. You should be talking to a radiation oncologist (RO), and not a urologist, about this. If you care to say where you are, someone may be able to suggest an RO nearby.
Posted 5/23/2015 4:49 AM (GMT 0)
Thank you Tall Allen. Am in Southern CA. Most recent PSA was reduced to 0.04. What a dramatic change from 29 ! Ultrasound did not indicate any modules, nor any visible presence or activity of cancer.
Posted 5/23/2015 5:03 AM (GMT 0)
Howdy neighbor! If your insurance allows you to see any doctor, go see my RO - Chris King at UCLA. He has a new "high risk" SBRT protocol - it only takes 5 quick treatments and you're done. LupronJim can tell you about it.

Also at UCLA, talk to Jeff Demanes about combination of HDR brachytherapy and IMRT (Dr. King manages the IMRT part for Dr. Demanes anyway, so you can ask him about it.) It's the more tried-and-true treatment. Either therapy offers good chances at a lasting cure.
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