DX today at 43.

Reading forum from few weeks. Found this really helpfull and a source of calm for this time. Just wanted to thanks all people here.

I had biopsy last Monday and today I've got results. If anyone can comment that will be great. 43 y old PSA 4

A LEFT APEX no malignancy
B LEFT LOBE adenocarcinoma Gleason 3+3 Number of cores involved 1/5 The size of largest focus 2mm Percentage of tissue involved in this specimen 3% Perineural Invasion No

CD Right Apex and Lobe Sections show single prostate core with scattered foci of HGPIN. A few foci show atypical acini of which immunohistochemistry is in hand.

Thank you.

Thank you Andrew. I do think they want me for AS for some time but this is good idea to wait? Today I'm bit confused. That was routine PSA test few months ago leading me to be here :)

I'm from London. Came here few years ago. You correctly read between lines english is not my first language. Trying my best here :)

It's surreal because doctor said cancer and I'm bit too optimistic. Thank you for your support and definitely will be educate myself on my journey.

Do think people are scared of the word Cancer and they shouldn't be. I also noticed some people trying keep distance once they know you have it. From the other hand you see others who are supportive as much as they can be.

Thank You Allen. That was pretty hard week for me. Biopsy was unpleasant but if necessery then you have to do this. No pain at all just uncomfortable. Just one issue after biopsy - bloody semen - but as I read here that's normal. Scary though. I don't know if in the Uk is any way to get second opinion but I will check this in the next couple of days. Will keep you guys informed. Maybe that's will help someone from UK as well.

Be Brave - Stay Strong - Stay Humble

If its confimed as a 6 by a pca pathology expert, AS is the road to take period. "most" younger men who get Pca get a higher ,hence more aggressive{aggressive is a relative term in cancer}i.e. in pancreatic its a completely different animal, as well as other cancers out there. If most of the men on this forum who were diagnosed age 60 or older…would have presented at 43…. with very similar stats as yours... what Im saying I s if you never had a biopsy or psa test for 15 or so year…you would present with a cancer that would still be "curable" Of course this is highly arguable..but the point I am making…is you can go on An AS treatment…clean up your act , if needed, {highly operative term..If needed...Forum is highly sensitive to my words}visa vis,, good diet…exercise, stress{exercise is a great stress mitigator} and maintaing a positive attitude. You theoretically could go for a long long time before treatment , if ever and if treatment is needed… you would still have a wide window of "curability" Good Luck.. My doctor was "Weird" about my reaction to diagnosis…but he was way of my short list for treatment anyway. Everything I have said is contingent on the validity of biopsy and volume...

Thank you all. Many great advices. Will do what I can to educate myself and go in the right direction. Yesterday I was like in dream or something but today I have to be realistic. It is bit mess in my case so apologies for you guys but I will be asking many questions here. Ok let's start from the beggininig.

My father at 64 got PC and after surgery he is alright (5 years passed PSA excellent). I was thinking to go just to check my PSA but I had also some symptoms of the prostate already. Few drops of urine after urinating and problem was slowly growing. My problems was more visible during winter. This year one more problem - sometimes after urinating I had feeling bladder is not fully empty. No other symptoms maybe just I had feeling like everything in the prostate area is bit stiff.

Ok second test PSA (different laboratory) show 4 so my Uro send me for MRI. Day before test I had sex (yuuuppi) and the Uro put finger to check my prostate half an hour before test. Week after MRI they send me for biopsy without consultation.

Ok yesterday nurse told me about biopsy results but also I discovered in MRI report my prostate is 50cc but the Uro during biopsy measured prostate and his findings are 25cc. Little confused. MRI advice was to send me for a bone scan but yesterday results are aggainst this. That was also something more in that report but like I said I never had any consultation about it. MRI report also said diffusively abnormal.

So here is a questions.

1. Should I have any symptoms from that small tumor? This is unlikely and maybe two things playing there. Cancer and prostatitis.
2. Can prostate can be on one imaging 50 and other 25?

Any wisdom highly appreciated. Thank you.

So sorry about your diagnosis and that you have to join us. But if there's some good news it's that your diagnosis is very mild (as far as these things go). That may not seem like good news to you, but it really is--there are tens of thousands of men (and probably much more than that) that are walking around with more cancer and are blissfully unaware of it. And the vast majority of them will be fine.

You've already been given some good advice upthread and I don't have much to add other than I would be looking hard at AS with your age and diagnosis. Some feel that younger guys shouldn't do AS, but I think the younger the better.

Regarding your two questions above, I can only answer #1 and that you really wouldn't have symptoms from your cancer. Even with a more aggressive cancer you probably wouldn't have any symptoms. (I was a G9 and never had any symptoms.) I don't know a ton about prostatitis, but I think it would be much more likely to cause urinary symptoms. (Of course, I'm not a doctor.)

Good luck to you and let us know how we can help. In general we're pretty good at flooding the zone when you have questions.

bio, with your low gleason score, it's unlikely your prostate symptoms (urinary difficulty, etc) are related to the cancer. Just be aware...and your doctors will know this...that the drugs that help with BPH suppress PSA, so your PSA will go down. This can mask the detection of PC.

I recall a guy in here a year ago who was from London, and he spoke highly of Guy's hospital and the physicians there.

Thank you Halbert. I read your story and admire courage of people fighting that beast. Yes I learned little bit more and it's seems like I can be extremely lucky. I found the beast really soon and have time to prepare also can start fighting now with good diet and other beneficial things. After initial desorientation right now I'm starting see positive sides of that. Found so many good advices here I can right now talk with my uro.

Thank you ASA. I have to learn so much more. I'm curious for example if they can find that small tumor and just cut that off? I'm worrying also that tumor is bigger and just needle spot the tail if I can say that. So yes bit anxious but I also see positives here like I said before. Need some time to fully understand all of that. And definitely need consultation with doctor to ask about differences on MRI and other things as well.

Thank you guys. You can reach me on www.jedstudio.me Last logo on main page I did this week.

biologiclondon said...
I'm curious for example if they can find that small tumor and just cut that off?

That's called "focal therapy," and if you are interested in looking into it, the two leading researchers in the world, Mark Emberton and Hashim Ahmed are at University College London. They don't exactly "cut that off." What they do is use any of a variety of methods (e.g., HIFU, cryo, FLA, PDT, IRE, etc.) to ablate the known tumor.

biologiclondon said...
I'm worrying also that tumor is bigger and just needle spot the tail if I can say that.

Aye, there's the rub. Prostate cancer is multifocal in about 80% of men. That means there are tiny bits of cancer spread throughout the prostate, many too small for detection by even the best imaging/biopsy. The success of focal therapy depends on what's called the "index lesion theory." That theory contends that all the small bits of cancer spread from the main tumor (the index lesion) and the bits it spins off won't then spin off new bits. There's some evidence for the theory, some against. My guess is that it's true for some men but not for others, and we don't yet know how to identify which.

At any rate, since you're fortunate to be in London anyway, I think you should try to get to see Ahmed/Emberton at some point.

- Allen

I was dx. at 42 and am now 50...same pathology but more cores positive. I had like 6 out of 52. all G6.

I going to put this to you as simply as possible....

What is the first thing you do when you buy rental property? Nothing!

That is exaclty the same thing you should do with your PCa......However, my PSA was 2.76...my brother had a PSA of 4 and was clean after a 52 point biosys......

Prostate cancer is just like the lyrics in that song "you don't know what you've go until it's gone." but in this case I would hold onto it for as long as I can.....