"Delayed onset" ED?

Three weeks ago my stricture was opened back up. (No problems on that front. I believe that's been properly and permanently fixed. It wasn't a bad one).

The trouble is....

about 6 weeks after surgery I was having pretty good erections even without Viagra. With Viagra they were about as good as pre-op.

I noticed that as the weeks went by i really began to need the Viagra more and it was producing not as good.results. After the stricture proceedure (3 weeks ago) I had some bleeding issues so I didn't really start trying to use the little guy until about a week ago. I can't get a hard on now even with Viagra. I've never had this issue before in my life that I can remember. So...it's beginning to weigh... i don't know what's wrong.

Has anyone else had a problem gettin' it up 7 mos. after surgery but no problems right after surgery?

I know my surgeon put in some kind of new stuff that's out that now that is supposed to stimulate the nerves and make woody come back faster. I'm wondering if maybe the effects of that stuff can wear off.

I'd ask him...but we're not on speaking terms lol.

I go to my "everyday" urologist Wednesday. I thought I'd ask him but you know how these guys can be sometimes. "Welll...ever things gonna be just fine". With some kind of a smile on their faces while not looking at you.

Didn't know if anybody here knows anything about that "membrane" they use now. Or...if anyone has had similar experience.

Thanks

I been thinking kinda along the same lines Bololidat. It's almost like some sort of a mental thing even though I'm having the arousal feelings enough for it to be working.

Lavitra. I'll find some. Thanks

island time said...
I know my surgeon put in some kind of new stuff that's out that now that is supposed to stimulate the nerves and make woody come back faster. I'm wondering if maybe the effects of that stuff can wear off.

Say whaaat?

"put in"...put in where?

Never heard of such a thing. Anyone else ever heard of this? Miracle Grow?

I'd darned sure what to know what that "stuff" is. You wondered if it "wore off;" quite the contrary, I'd wonder if you are now having a side- or after-effect from it. Or moreover, I wonder if he was feeding you a line...or joking with you. Did you sign a release before surgery for experimental meds (you would have received a copy with your discharge papers)?

You have a written copy of your surgical report, right? Absolutely everything (starting with your dosage of anesthesia) which was done during the procedure will be listed there.

Please let us know what you find...

It can take awhile to recover and a bit of work.
But I am sure something good will come up.

Andrew

island time said...
It'll get read. :)

Wow! Thanks for sharing. I had not heard of this for RPs! I'm fascinated!

So, you probably know all about this already, island time, but I don't recall earlier discussion on this anywhere at HW/PC; has there been, or are you the first? A HW/PC pioneer? Anyhow, I learned a few things here in the last few minutes which I'll share, but I'll ask you to add/fill-in as needed...others may be interested in this in the future

The Amniotic Membrane (AM) is the inner layer of the placenta that surrounds the baby during pregnancy, and consists of the amnion layer and chorion layer. Tissue is gathered via elective "donation;" donor eligibility requires a live mother to have given full consent and to have delivered a live birth via elective Cesarean section. (There's actually a business formed that is in the market to collect and re-distribute these.)

While the basis for this therapeutic effect has not been fully elucidated, native human amnion/chorion membrane contains an array of growth factors that are known to play critical roles in the physiological processes leading to normal wound healing and tissue regeneration. I've previously heard of this being used for burn healing, but the idea to improve continence and potency recovery is new in the last few years...a study paper presented at the World Congress of Endourology in 2014 was claimed to be the first-ever.

The study's author, who said that the procedure is not particularly challenging but that there is a definite learning curve, gave this interesting description at the presentation:

"Once the prostatectomy is completed but before the urethral anastomosis is conducted, the membrane is passed to the site via a 12-mm side port,” he explained. “My assistant rolls up the membrane, which is like parchment. It has to remain perfectly dry as it passes through the port because if it gets wet, you can't handle it. I grab it with the robotic arm and depending on the thickness and width of the neurovascular bundle, it can be placed as one sheet or if the bundles are wide apart, it can be cut into two sheets.

“It is wrapped around the nerve. The moment it gets moist, it sticks. There is no need for sutures. The sides are labeled 'up' and 'down.' The 'down' side goes onto the nerve. Otherwise, it will not stick."

Very interesting!

Did you have this done in Florida by Dr Patel (I see his name pop up a lot with this topic)? You also had the iatrogenic PSM, as I recall, right? As I said, others may be interested in learning more about this new technique in the future...

Thanks, island time.

I hadn't heard of anyone else having dHACM (dehydrated human amnion/chorion membrane) during RP...have you? Does anyone know of anyone else who's had this?

I did a search on HW/PC on "dHACM" and there were no results, so I extended the search more generally to "Amnion" and I did find one thread, which was an overview from Tall Allen last year titled "The womb continues to protect us" with the same link you provided. Here's what Tall Allen said last year:
www.healingwell.com/community/default.aspx?f=35&m=3399480

I entered "dHACM" & "prostate" into the search at the clinicaltrials.gov site and found two; both are randomized studies. There's a clinical trial to examine the benefits of dHACM during RP which is recruiting patients (Dr Patel running this one): /clinicaltrials.gov/ct2/show/NCT02526173

And another one to learn about safety and effectiveness of dHACM during RP which says it is not yet recruiting (at MD Anderson): /clinicaltrials.gov/ct2/show/NCT02645591?term=DHACM+prostate&rank=1


I think it's a fascinating new development. I think it goes to show how the process and techniques are continually changing and improving over time. It goes directly to the point Dr Ian Thompson made: "if you have a choice of a dollar today or a dollar 10 years from now, take the dollar today. But if you have a choice of a curative treatment for prostate cancer today or a curative treatment for prostate cancer 10 years from now, choose it 10 years from now."

Post Edited (JackH) : 6/6/2016 4:45:14 PM (GMT-6)

I find that I've never had a problem since surgery when partnering up with a cooperative wife. But over the last 4-5 months , when I am forced to be left to my own devices, failure lurks. Erection is attainable, but I can't seem to get to the finish line. That hadn't happened the first year r so after surgery.
So IT I guess I'd call it late onset situational ED. Maybe I'll coin the term LOSED.

@cmetalman, no laughing matter, but that Mr Softee comment was pretty funny

IT, hang in there. I am sure you'll get it straightened out soon...

Andrew

Pratoman , I'm glad I made you laugh . Now I'm going to send you some famous Phillies "soft" pretzels .
Cmetalman

I continue to be fascinated by the new use of dHACM (dehydrated human amnion/chorion membrane) during RP.

I previously linked to the ONLY other HW/PC thread I could find with even a mention of it...it was an informative post by Tall Allen (see link above) about a year ago when the first medical studies were released. In the final comment of that post, Tall Allen asked: "I can only conjecture at how he arrived at dried amniotic sac for use in this and where he got them."

It turns out that there is a small industry which has grown up around this...the use in RPs is brand new, but dHACM use in the last decade for burns, ocular, dental, spinal surgery and wound healing has, apparently, flourished.

For those who may be interested, here's a piece of marketing literature which describes one company's growth:

On January 5, 2011, the company acquired all of the outstanding equity interests in xxx, LLC, and subsequently consolidated the corporate offices and operating facilities in yyy. This strategic acquisition brought together amnion tissue processing technology with zzz's experienced management team and extensive distribution network in order to position the company for market opportunities across multiple areas of medicine. After nearly two decades of human tissue experience, the xxx founders had the vision to apply modern proprietary processing techniques to placental tissue to create unique ophthalmic, spinal, orthopedic, and dental implants.

At the time of the acquisition, xxx distributed tissue in several different membrane sub-segments, such as ocular, dental, and spine. Early 2011, zzz launched abc® for applications in spinal procedures. abc® is used as a barrier membrane that reduces scar tissue formation between the dura and soft tissue. During 2011, the company launched def® nationwide. def® is an allograft specifically processed for acute and chronic wounds. The company further expanded its amnion product offering in 2011 with the introduction of abc® Wrap for both nerve and tendon protection applications.

fascinating

What happened here...?

island time said...

I'd ask him...but we're not on speaking terms lol.

I'm not sure from your "lol" if you are kidding or not...


Was this due to the iatrogenic PSM (accidental slip of the knife causing a positive surgical margin)?

JackH said...
What happened here...?

island time said...

I'd ask him...but we're not on speaking terms lol.

I'm not sure from your "lol" if you are kidding or not...


Was this due to the iatrogenic PSM (accidental slip of the knife causing a positive surgical margin)?

No. Accidents happen. I understand that.

It's due to him telling me that the accidental slipping of the knife doesn't change my prognosis. And my asking him where he's getting that information offended him and not telling me. It's also due to the fact that the sutures coming lose were "my own fault" for sitting down in an uncomfortable recliner the day I got home from the hospital. That's pure BS. I didn't sew up the sutures. He did. And a particular brand of recliner has nothing to do with whether or not sutures come loose around a badder neck.. He's got his story, I've got mine. I think i know how both happened. I believe they're related. And i have my resaons for believing this.

I won't reply anymore to this topic.

This weekend is Father’s Day.

JackH, I thought your suggestion to island time was spot on, and I agree that he has “a powerful story” to tell favorable-risk newcomers about the slippery slope.

Linking these two points (Father's Day, and the suggestion to island time to pay-it-forward) together, I’d like to share with you a HW/PC thread from 5-years ago which I ran across which have two excellent posts…

Dan Zenka, who was then VP of Communications with the Prostate Cancer Foundation (PCF), started the thread titled, Pay It Forward This Father’s Day with the Gift of Information.
Link: https://www.healingwell.com/community/default.aspx?f=35&m=2138970

Dan asks men, on Father’s Day, to ” make it a point to open the discussion and help make prostate cancer something to talk about. By passing it forward, you’ll be helping so many other men…”

Another excellent post from Casey59 follows in that thread shortly after Dan's which explains the concept of pay it forward from the 200+ year old words of Benjamin Franklin. I won’t copy/paste it here, but encourage you to use the link above and read both posts for yourself...this is one of the all-time best at HW/PC.


Whatever your story…pay it forward this Father’s Day.
-Norm