is there a down side to trimix,et al...

The answer to your question is mostly no with a possible quibble. For the most part, trimix is good for a man's erectile tissues, keeping them better oxygenated and keeping the stretchy bits stretched. If it works well it also helps a man with his confidence. The result of that extra confidence is that he is more likely to still be active when and if his natural erections return. Lots of men never recover because it takes a long time and before they get there they have given up.

The quibble is that some men (and a very few doctors) worry that the injections may contribute to scarring and possibly can contribute to the development of the hard "plaques" that cause Peyronie's Disease. It is sort of hard to tell if that is true. Men who have had prostate surgery are more prone to PD as a group and the subgroup of them who are also using trimix share in that increased risk. This means that they are much more likely to develop PD than the overall population but how they compare to other men who have had prostate surgery is hard to say since the available populations are small compared to the number of men you would need to achieve statistical significance.

I would agree with PDA.

I've been using it a mix of a few times a month as part of rehab, as well as for what it was intended for, and have no apparent side effects after 5 years. Yes, a couple of aborted trips to the ER when I pushed the dosage, but I know better now. Be happy with what works ....

Now we do need to remember that there have been guys here who pushed it to 20+ times a month, even multiple times a day, and they have had problems / complaints. But for me it is the golden egg, and I'm not about to tempt fate.

Now that I have to pay 100% retail out of pocket, and it is less important with the Lupron / XTANDI mix, I'll need to remove myself from the study pool.

Appreciate the replies. 5 years without S/E's is meaningfull...Wishing you well in all ways 142....

Fuelguy1...You nailed the answer to my thread....succinctly

NortehrnLights,

Sometimes the end of the needle is in-between the blood chambers and when you inject it forms a small lumpy pocket of medicine in the tissue. Generally, the meds will eventually leak out and the lump will go away. Usually when this happened to me I would also notice that the meds wouldn't work very well. (If the meds aren't where they are supposed to be...)

I found that I could avoid the problem by pressing lightly on the plunger to make sure it moved easily. If it was a bit balky then I was trying to inject into the wrong place. All I needed to do (usually) was to press the hub of the needle a bit harder against the skin to get another quarter inch of penetration and try again (I used really short needles). Once or twice I needed to try a second spot.

Post Edited (PeterDisAbelard.) : 8/16/2016 3:29:35 PM (GMT-6)

A little flip of the quote from 142 for my 6 years with Trimix:

"Now we do need to remember that there have been guys here who pushed it to 20+ times a month, even multiple times a day"

Yeah that's me at times -- not even using each one for intercourse -- sometimes just for having 'nocturnals' -- for most of the night like when we were 18 -- something for the missus to hold on to.

"and they have had problems / complaints"

And for me never any problems or complaints -- over 1100 shots now by my estimate -- all good .. never an ER visit .. shaft still perfect straight -- no tough spots.

Just once I thought I might have to do something at near 4 hrs -- that was my first shot from the darned Uro -- .30ml when it turned out .10 was fine later.

Good stuff and still pretty cheap.

J