Darie said...
Thanks Dan .but yours is nadir and stable. Mine was nadir <0.003 and rising.how long you were on Lipron before it failed and what your scans found,,?
Thanks.
So you have increased to levels that would still be undetectable by the lab I use, where undetectable is < .01. The guys that did my surgery 4 hours away at Vanderbilt University high volume RP center still only did standard PSA, where they called anything < .1 undetectable and won't consider doing anything until it reached that level. Actually, my local guys who are monitoring me, and who do the more sensitive test, feel the same. They don't normally recommend taking action until .1. I have heard it said that doubling times based on the ultra-sensitive do not really give us much useful info. So it is quite possible that you are not yet on a clear trend upward. Though there are some studies that indicate that once you finally reach .03, your odds of some day actually hitting the official BCR ( .1, .2? ) are quite high.
But, of course, your story is different as you ave already BCRed I presume(at what PSA level?), since you have had SRT AND mets already. But would you give some more info about
your original surgical path? I see you were the "good" Gleason 7, i.e. 3+4. But something about
a 4 at 15%? With nodes negative. Were you also negative for seminal vesicles(SV) and negative margins? The reason I ask, I also notice you had salvage RT within 1 year, which also "failed". That seems an exceptionally poor out come for a G3+4 with a totally negative surgical pathology. Was there anything else not good, like + margins or SV? Just curious.