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Seminal Vesicle Involvement

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Posted 12/6/2017 1:26 PM (GMT 0)
Hello
I would like to ask if
Seminal Vesicle Involvement (post surgery)
has more poor prognosis than Lymph Node Involvement?

Post Edited (Smara) : 12/6/2017 6:29:57 AM (GMT-7)

Posted 12/6/2017 2:17 PM (GMT 0)
I believe that lymph node involvement is worse.
Posted 12/6/2017 2:55 PM (GMT 0)
SVI is not good either. I had it and two years later I had lymph node mets.
Bob
Posted 12/6/2017 6:39 PM (GMT 0)
Smara-

Please share the details of his pathology report.
Posted 12/6/2017 10:44 PM (GMT 0)
Smara,
have you been treated for PC? This is how PC progress in a man if he is not treated (it could answer your question):

PIN --> localised --> locally advanced --> N1 --> M1 --> CRPC --> death

Seminal Vesicle Involvement (SVI) - is in "the locally advanced phase"
Lymph Node Involvement (LNI) - is in "the N1 phase"

so LNI is more advanced than SVI and hence harder to treat.
Posted 12/6/2017 11:07 PM (GMT 0)
My husband 64, post de vinchi surgery with bilateral SVI, no LNI, negative margin, extra-capsular
Gleason 4+7.
His seurgon said, no other treatment need
for now. Is this bad news? It's mean the
cancer will come back with LNI? Why no
other treatment need?

Post Edited (Smara) : 12/6/2017 4:14:57 PM (GMT-7)

Posted 12/6/2017 11:25 PM (GMT 0)
Smara,
its very possible that they have taken out all cancer when they did surgery so till they have any other compelling reason they are recommending no further treatment. When pathologist dissected the removed Seminal Vesicle (SV) they found cancer - hence SVI is positive and its great news that they did not find any cancer in the lymph nodes (hence LNI negative). Since you have negative margin, the hope is no cancer escaped or is remaining although it was locally advanced( it went out of the prostrate to the Seminal Vesicles).
The only way to figure out next steps is to monitor PSA regularly and hope it does not go up.

In the meanwhile based on your information you can calculate chance of recurrence using this nomogram - I dont know your initial PSA so cant do it for you:

https://www.mskcc.org/nomograms/prostate/post_op[url]
Posted 12/7/2017 2:09 AM (GMT 0)
Thanks for explaining. So far as you know right now, he is cured. But he has to monitor it with ultrasensitive PSAs every 3 months to make sure it doesn't come back. He has no lymph node invasion, which is good. He did have seminal vesicle invasion, which is a risk factor. That's why they have to watch closely.
Posted 12/7/2017 4:58 AM (GMT 0)
Thanks a lot to all of you.
for the nformation and support.

Post Edited (Smara) : 12/7/2017 6:52:17 AM (GMT-7)

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