Side effects of Arimidex with Testosterone Supplementation

Hi Gang....long time, no see here for me. I have recently been having extreme bone and joint pain in the last 18 months. Couldn't figure out where to pin the difficulty as I had been running and doing weight training, pain free for quite some time. But a breast cancer survivor who knew my history asked me if I was still taking Arimidex to limit estrogen conversion with my TRT. I said yes, and she then asked if I was taking any calcium, D3 or bone density supplements such as Boniva. I said no. She said that she was prescribed Arimidex after her breast cancer treatment, and her doctor prescribed Calcium, D3 and a bone scan yearly. Could have knocked me over with a feather. I have had knee pain, hip pain, shoulder pain as well as TMJ and trigger finger problems. All related to joints. Online research I've done indicates that Arimidex causes a lot of problems in joints. Has anyone experienced this? For newcomers, I have been on testosterone replacement therapy for 7 years now following surgery for PCa. PSA still undetectable!.....any help insights would be appreciated, Thanks!---Arnie

Thanks, JNF. Similar stories from other women on the AI's.... I indicated that I hadn't taken any supplements; actually, I've been taking a daily D3 for some time now, but that didn't counteract what I've been experiencing. Since I posted, I contacted my compounding pharmacist and ran the scenario by him. He said that although I wasn't on as large a dose as breast cancer patients would be, there's no telling how one's chemistry will work. His suggestion was to try a natural AI called Chrysin (which I have tried before with no result), but he said they could compound it. The reason that oral Chrysin doesn't work is the it's diluted due to passing stomach and liver obstacles. This would be applied transdermally on the scrotum so it's absorbed directly. He said it's effective (maybe not as lethally effective as Arimidex or other AI's) but it's something he thought I should try. Anyway, thanks for the reply, and I'll keep you posted---Arnie

My wife was diagnosed with breast cancer in 2010. She was put on Arimedex and had really bad joint pain. She stopped after a year. Couldn't take it anymore. Had a hip replaced 2 years ago. Not sure if there is a connection. She thinks there is. It was a very small amount of cancer found after a breast reduction. No recurrence since.