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Posted 1/25/2019 1:50 AM (GMT 0)
My brother's spa is now .1

I am so nervous

Could it be he has just not hit Nadir yet???

Again diagnosed june 2017 gleason 4+3
Psa was about 4.56
No mri or scans done
Radiation and ADT

After .01
Then .02
Then .09
Now
.1
Brca 1 family mutation

Still no need for concern??
Posted 1/25/2019 2:30 AM (GMT 0)
Is he still on ADT? What kind? Has he seen a MO?
Posted 1/25/2019 4:45 AM (GMT 0)
Is he still on ADT or has that stopped? You'll see a PSA rise as the ADT wears off. Could be normal. Need more info.
Posted 1/25/2019 7:56 PM (GMT 0)
No longer on ADT
Forget exact stop date
Posted 1/25/2019 8:14 PM (GMT 0)
Wow. Just realized I think I was misunderstanding Nadir.

Is Nadir when your PSA drops to hit Nadir?

I thought it rises to Nadir.

Now more reason for concern?

.01 to .02 to .1.
Posted 1/25/2019 8:24 PM (GMT 0)
Once ADT stops, it's not unusual to see a (slight) increase in PSA. The question is, over a period of several months, does it stabilize or keep rising? What are the dates for the PSAs you mention?
Posted 1/25/2019 8:25 PM (GMT 0)
The opposite of nadir is zenith. It's peak level would be the zenith.

So... now it looks like EVERYONE is starting threads on 'no subject'.

I must have started a trend. But don't let these posers fool you.

There is only one original. Then they broke the mold... okay, J/K.
Posted 1/25/2019 8:28 PM (GMT 0)
nadir is the lowest PSA reading recorded to date. Post ADT, PSA can be expected to rise a bit. Post RT recurrance is considered nadir + 2.

Everything is fine, normal and reason for a party.

Andrew
Posted 1/25/2019 10:10 PM (GMT 0)
ok. In the shop, are you saying .01, .02. 09 then .1 is still ok?

Exact dates. Not sure.

First after a few months of ADT and Radiation Finished .01
3 mos. later .02
3 mos. later .09
3 mos. Later .1
Posted 1/25/2019 10:38 PM (GMT 0)
ADT was keeping the PSA down. Once that stopped, PSA started to rise. It will level off.

and the difference between .09 and .1 is .01 - statistically meaningless and effectively the same.

Sounds fine to me.
Posted 1/25/2019 10:43 PM (GMT 0)
Thank you so much. Bless you. I need to hear that now.

One less thing to worry about at this time.

Have an amazing weekend.
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