New symptom: pain and swelling in thigh?

Hello,
My dad told me he is having pain in his thigh now and he told.me tonight it is swollen up. He keeps telling me it's "in his muscle" and it's because he has been laying in bed too much but I tend to wonder. His latest medication failed and there are no more pills to take. He has to go on to chemo now. The doctor said his PSA is up. We didn't even ask the number because we don't even want to know anymore. He had his scans 2-3 months ago with no bone mets but 2 small lymph nodes showed positive. The doctor said they were very small and that they grow very slowly. I guess I am just wondering if there is a typical place that the first bone mets start or is that different for everyone, and could it go from nothing in the bones to swelling in only a couple of months? I know nobody can tell me with absolute certainty about his particular situation, but I'd like to know the typical scenario, if there is one. Thanks!

Hi Rockyfords,
Thanks for your reply. Do you know if that is from the PCa treatment or the PCa itself? I researched what you told me about your blockage and I got this:

Lymphedema refers to swelling that generally occurs in one of your arms or legs. Sometimes both arms or both legs swell. Lymphedema is most commonly caused by the removal of or damage to your lymph nodes as a part of cancer treatment.

Best wishes to you Rockyfords.

Lisa,

I'm sure you already know that circulation problems in the legs, especially blood clots, often go along with spending too much time in bed. I imagine your dad knows it, too. If he spent more time being active he'd feel better. And, of course, if he felt better it would be easier to do more. That's the maddening thing about dealing with loved ones who are depressed -- the vicious circle, the less they feel like doing the more depressed they get and the more depressed they are the less they want to do. You know that if they could just somehow get over it -- break the loop and get out and about and do stuff -- the depression would let up and they'd be over it.

You've mentioned before that your dad is being treated for the depression and is still struggling. The only hopeful thing I can say is that depressive episodes don't last forever. Sooner or later depressed people usually seem to bottom out and start to get better. Once things turn around the vicious circle turns into a positive reinforcement loop where the more they do, the more they realize they want to do, and they gradually feel better.

In the meanwhile take care of yourself. Keep us posted and we will continue to offer sympathy, company, support and highly questionable opinions on things medical.