HealingWell
Search Close Search
☰

PSA 40.0 to 3.79 in two months

Support Forums
>
Prostate Cancer
✚ New Topic ✚ Reply
❬ ❬ Previous Thread |Next Thread ❭ ❭
Posted 6/18/2021 11:54 PM (GMT 0)
My first-alert PSA was 40.0 on April 15 this year (2021). Ten days later it was 31.0 on a re-check. (I had quit the scotch smile I radically 'improved' my diet/exercise as reported in another thread here and started ADT on May 26 (four weeks ago). Today (June 18) I had an appt. with my GP (for newly discovered mild ostopenia) and requested another PSA in order to have some kind of baseline before starting EBRT Monday (June 21). My new score is 3.79! Any ideas about to which factor that should most likely be attributed? Diet change? ADT? Divine intervention? I realize, of course, my 12 of 14 positive biopsy needle cores trump my PSA in any case, but still curious nevertheless.

PlatoK
Posted 6/19/2021 12:00 AM (GMT 0)
HI PlatoK. My answer is (B) ADT.

If you haven't already, could you please create a signature? It will help folks be more specific in their replies. And it will save you having to keep answering the same questions about your history and status.

Thanks,

Djin
Posted 6/19/2021 12:08 AM (GMT 0)
Yes sir,
Your PSA drop is certainly due to ADT, and no other reason.

Good luck with your RT!
Posted 6/19/2021 1:23 AM (GMT 0)
Totally a result of ADT and 3.79, while a big I,prove,emt, isn’t low.
Posted 6/19/2021 2:51 AM (GMT 0)
Will try to create signature, as advised.
Posted 6/19/2021 12:03 PM (GMT 0)
Diet and exercise has never shown in any scientific studies to have the significant effect on PSA that you are citing. It is clearly the ADT. What specific ADT medication was administered? Lupron, Eligard, Firmagon, Casodex, or other?

After starting ADT my PSA went from 59 to undetectable in less than 90 days. Yours should as well. That you reduced from 31 to 3.79 in three weeks is right on track and to be expected. Didn’t your doctor explain this to you?

With 12 of 14 positive cores and PSA over 20 you clearly have a large amount of PCa. That it went from 40 to 31 indicates possible infection as well. Did you have any antibiotics during that time? Were you given a course of Casodex before the ADT shot? That could explain the first reduction from 40-31.

What are the other results of your biopsy? Gleason grades and score by core? Percent involvement by core? Results of nomograms, etc.? That you are starting EBRT, that means you ruled out surgery. Are you also having a brachytherapy boost? How many fractions of EBRT are you scheduled for? Are they radiating the pelvic lymph nodes based on your clearly high risk situation? What prompted you PSA test? What is your age?

Providing specific information like this will help members provide good information rather than just guessing and asking more questions.
✚ New Topic ✚ Reply