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Posted 4/27/2022 6:55 PM (GMT 0)
I’m just back on ADT with Lupron and the hot flashes are back in full force. I had been taking Oxybutin on my last ADT session and at first it seemed to calm them down quite a bit. Is there any new treatment for these dang things? Has anyone been on Provera? Did it help? Thanks in advance.
Posted 4/27/2022 7:38 PM (GMT 0)

Turner 2 said...
I’m just back on ADT with Lupron and the hot flashes are back in full force.

My final Lupron shot was four years ago, yet my testosterone never recovered. Fortunately neither has my PSA. But it looks like I'll be having these hot flashes forever. My urologist does not want me supplementing T, and my GP does not want me on any form of female hormones. Sort of caught in a tight spot.

After some research, I started taking PM (Pueraria Mirifica), an OTC plant based phytoestrogen that is supposed to help with post menopausal hot flashes. It's only been two weeks so far. The only SE is said to be gynocomastia... well that ship has already landed. I see my GP next month and will see what he says about it.

I am still taking venlafaxine, which I believe has helped reduce the frequency and severity of hot flashes, but has done wonders for my moodiness. I'd like to say I never get angry, but nothing really bothers me anymore.
Posted 4/28/2022 12:25 AM (GMT 0)
I don’t mean to sound like a GNC Rep, but for what it’s worth when I started having HF from stopping my Testosterone injections thst I had been taking for 25 years for low-T, a menopausal aunt recommended Black Cohash. ***? Why not? HF stopped. I’m now on Eligard injections (every 6 months for 2 years) and no HF. Just my two cents.
Posted 4/29/2022 5:49 PM (GMT 0)
I had a 6mo lupron shot in march..
I kind of have a question i guess..

My dad, who died of PCa, had his testicles removed at the end. I remember talking to him on the phone and he said how remarkable it was that he had absolutely no interest in females at all.

So now me.. I get the shot, and I am waiting for this glorious moment when females have absolutely no power over me. It hasn't really come. I think female interest is reduced a bit. I get the hot flashes. Quite a few.

Guess there are many different ways people react to ADT?
Posted 4/29/2022 6:31 PM (GMT 0)
Isitserious, I am glad that Black Cohosh is working for you. I looked into getting some, but it said it could cause blood clots in the legs. Since I already have PAD, I guess that I shouldn’t try it. It says to watch out for liver problems. One site says to not take it for more than 6 months and another says up to one year. In any case, I hope it continues to work for you.

groundhogy, LOL, well my libido is gone after 6 months on Orgovyx. My wife still reigns supreme and that will probably never change. I will say my breast are giving her breast a run for the money. So maybe in that area I will gain some power over her. LOL. My best to you.
Jack
Posted 4/29/2022 6:32 PM (GMT 0)
I dealt with a serious lack of libido 25 years ago just from Low-T. Weekly T-shots fixed that nicely. Having to quit the T-shots when I got the PCa Dx killed the libido again. Can't say I'm happy about that (nor is my wife) but ADT seems to be the standard treatment for PCa these days (other than having the whole thing removed and I don't think the results sound much better). Now getting Eligard injections haven't helped things.
Posted 4/29/2022 7:03 PM (GMT 0)
Low dose estradiol skin patches can very effectively stop almost all of the side effects.

0.025 to 0.050 mg/day patches can be enough. Dr. Charles Myers used them with his long term ADT patients.

I’m on a higher dose, and feel absolutely terrific.
Posted 4/30/2022 2:01 AM (GMT 0)

Turner 2 said...
I’m just back on ADT with Lupron and the hot flashes are back in full force. I had been taking Oxybutin on my last ADT session and at first it seemed to calm them down quite a bit. Is there any new treatment for these dang things? Has anyone been on Provera? Did it help? Thanks in advance.

Hi Turner 2

I started with Venlafaxine 1st for 6months it started to fail after 6 months. My Uro switched me to Gabapentin @ 1200 mg daily. This has worked great for the last 4.5 yrs. I am still on Lupron shots and will be for life. I wish you the best at finding relief.
Posted 4/30/2022 3:50 PM (GMT 0)

groundhogy said...
I had a 6mo lupron shot in march.. I kind of have a question i guess... My dad, who died of PCa, had his testicles removed at the end. I remember talking to him on the phone and he said how remarkable it was that he had absolutely no interest in females at all.

So now me.. I get the shot, and I am waiting for this glorious moment when females have absolutely no power over me. It hasn't really come. I think female interest is reduced a bit. I get the hot flashes. Quite a few.

It was about five weeks as I recall, after my first shot before the hot flashes started. It was not much longer after that when I stopped having any sexual thoughts. It does indeed feel odd after a lifetime (well, 40-50 years) with constant thoughts of women and sex. It will hit you, maybe not all at once. It's more subtle. One day you realize that women just seem.... well, odd.

BTW I'm considering having my single remaining testicle removed while I'm under anesthesia for my AUS replacement, since it no longer produces testosterone. I'll be speaking with my urologist and with the urosurgeon who will be doing the surgery (because after radiation it's not as straightforward as it was five years ago). I may ask my GP about seeing an endocrinologist beforehand. Not sure yet.
Posted 5/4/2022 12:38 AM (GMT 0)

Redwing57 said...
Low dose estradiol skin patches can very effectively stop almost all of the side effects.

0.025 to 0.050 mg/day patches can be enough. Dr. Charles Myers used them with his long term ADT patients.

I’m on a higher dose, and feel absolutely terrific.

I have been on the 0.25 mg patch for 2 years, they helped me a lot.
Posted 5/4/2022 3:44 PM (GMT 0)
Red Wing & Duck, how are your boobs doing with estradiol? Any issues?
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