After 6 years, I think I'm detectable need advice.

get retested and remember you are a G6

Labcorp's uPSA test does not return a true zero when a test solution with no PSA whatsoever is run, but rather some small, positive number that ranges up to what is called the Limit of Blank, which is not far below 0.006 for Labcorp's test, if I remember. There are non-prostatic tissues, like the urethra and Cowper's glands, that can produce minute amounts of PSA. Your previous <0.006 may well have been very close to that value, so that either your daily fluctuation or the imprecisions of the test assay put you right at 0.006 on the day of your last test. You should not be worried and, IMO, you do not need a retest before your next regularly scheduled test.

In addition, an independent laboratory put the Labcorp test through rigorous testing in ideal conditions. A solution with a known concentration of 0.010 ng/mL of PSA was tested 20 times. The results had a 2 standard-deviation range of 0.010 ± 0.002. In other words, if your PSA were, say, 0.005 on any given day, 98% of the time your measured result would fall in the 0.003 to 0.007 range (assuming the test could report values below 0.006, which it cannot). So you could get back a detectable result (0.006 or higher) even if your actual PSA were actually still below 0.006!

Considering (a) one's natural PSA fluctuation, (b) the inherent limits of the test method, and (c) the fact that lab conditions (sample prep and machine calibration) not always ideal, a uPSA of 0.006 six years post-surgery is still about as good as it gets!

Djin

To everyone who took the time to reply, I greatly appreciate it. Definitely has put my mind at ease a bit. Cyclone-ISU, still remember your response to my very first post 6 years ago while I was lying in bed still with the catheter in, a few days post prostatectomy. The information and support you guys provide here are absolutely invaluable. Hope you all know that.

Crusher 10833,
Calm down, you are most likely still undetectable. They probably forgot to print the < sign. I am 99.99%sure but see what the DR. and a retest says. Also 99.99% of us would love to be .006.
Wings

Remember there is no true zero PSA. You have a long way to go before any recognition of a PCa recurrence. You are very young for this and have to stay diligent, but not to worry about it. Keep testing, potentially more often for a while to see if a trend develops that would indicate more investigation. Right now there is no test or scan that would find anything at your low ultra low PSA, so don’t fret.

Don’t worry, be happy…….as the song tells us.

Dude. chillax. No offense meant but you are being ridiculous. You lost your >. ? Really? You're a G6!! If there was anyone who ever needed to worry it wouldn't be you.