have a question about psa increasing, but no mets

Chemo may still not be the best choice yet from what I understand, and there some guys with a better understanding her on HW. I believe there may still be some HT tricks in the bag.

I would second the advice to find a major cancer center and get some top notch help.

Have you said what part of the country you live in ?

I understand from some of the Canadian guys that Edmonton has a really great prostate cancer center.

It may be worth it to you guys to make a trip down into the states to Mayo, Cleveland Clinic, or Johns Hopkins, just for getting in to see a cancer speialist to get some direction for your choices in Canada.

You may want to open a thread entitled Canadian looking for some assistance, and get some of our Canadian guys to help out here.

Best of luck, and keep on posting here.  You will find some help.

Agree with John T, as I feel cloned at times (lol) we apparently have alot in common with reading Dr. Strum and others. Once you are hormone refractive, insensitive (those drugs stop controlling psa levels) and such wording, you are in the domain of oncology if you wish to treat the PCa further. The best scenario is likely to find a PCa oncologist.

As for chemo on PCa the generalized thinking is it is not all that wonderful and is not considered at all curative for PCa cases, it is palliative and perhaps useful for some time frame...some published information puts that into months and not years. Big decision if you are going to use such. There is alot better control with fewer side effects than chemo (it appears), you have to look at everything out there and I have posted before the many types of drug therapies used against PCa, you may have to search hard and outside the 'box' but alternatives are available to use. Contact: www.paactusa.org for info on such.

Andrew that is a fact PCa is less than science to control it, it becomes more of an art. An oncologist is an artist as using drug therapies and related things on a biology level. Alot of these drugs work on most patients(how well and how long is the unknown), but for some it could be hardly effective in some cases...thus the variants in the gleason scores, the plodity analysis of the PCa cell structure (diploid be best type to be found with) etc....etc. Patients immune system, overall condition could also be factors in this mix.