Any thoughts on clinical trial with IMRT?

I will start IMRT next week, but met the radiation oncologist yesterday and was impressed with both him and the facility. Not as sterile as a hospital or surgery room. But he said that I was eligible for a clinical study due to reocurrence and the computer would pick betwenn HT with 2 shots at 3 and 6 months or have HT and radiation to the prostate bed and to the pelvic lymph nodes as well as HT.

I am a T2C with extraprostatic extension with both conventional acinar adenocarcinoma and prostatic adenarcinoma.Left lateral and left posterior margin invovlement. Less than 105 involvelment. Right and left seminal vesicles negative for malignancy. Any feedback is appreciated. My first thought is I dont want HT but my second thought is I want to live as long as possible.

Thanks

Michael

There are a few studies that show significant survival benefit for RT + HT. HT is administered for two months prior to RT, during the RT and for two to six months after. Unfortunately, these studies are for primary treatment.

My Rad Onc said that there was a new study (that I was unable to find so far) that shows even better result with longer HT period (3 years) after the RT. That study, while not exclusively for SRT patients, at least included some of them.

The study you are talking about sounds like exclusive to SRT folks. This is great, I wish the results of this were available today.

I had a recurrence (I am a T3b with G7) and chose RT plus HT. I am two months after completion of RT. The agreement with the doc is I'll do six months of HT and then we discuss if any more is needed. I am not enjoying the HT, but it is not bad. Hot flushes and complete loss of libido are the main complaints.