I had similar scenario back in 2004 while on ADT3 with slightly consecutively (8) rises, then went with different therapy. You could try the casodex and see if blocking the T made from the adrenal glands is helpful or not. If I remember right you did have some risky original stats? I was getting psa tests monthly way back then and could see what the trend was early on and made a big switch from ADT3...worked well in my case. If you are say starting to fail on Lupron this early, it is alittle more worrisome and you may have to switch to various options, perhaps in sequencing methods in order to control the PCa and psa esculations. A good oncologist who is
open minded could be your pal in this.
Dx-2002 (Mar-Apr) bPsa 46.6 12/12 biopsies all 80-95% PCa, total urinary blockage and was in emergency room just prior to seeing uro-doc, Gleason scores found 7,8,9's (2-sets like that almost all identical parameters too), ct and bone scan appearing clear, panic situation grabbed internet, books and got 8 opinions+, ADT3 (by my demanding it), neo-adj. to radiations: Neutron (10-sessions) & IMRT-Photon (24 sessions) Oh-denied surgery by Dr. Menon (righteously advised too), ADT3 total for about 2 years. Fired uro-doc (2004) and quit ADT3, DES only and intermittently ever since. Cost about nothing, fabulous results and basically like no side effects...no thank you cards from my insurance company saving them $13,000 a year for 7 years? Gee I went against the wisdom of my uro-doc...place me before the firing squad I should not be allowed to have choices 
His cash cow left the building and been singing with Elvis every since.
Sailor- I like you and your are a heck of a helm's men, maybe look outside the box get another opinion from independently found onco-doc type? We are rolling the dice in this anyway, no guarantees or warranty programs, lots of money being made off patients which is obvious.
Post Edited (zufus) : 7/30/2011 11:05:26 AM (GMT-6)